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Project title

Comparative assessment of social-ecological resilience and transformability to limit antimicrobial resistance in One Health systems (AMResilience)

Funded by the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR), via the Canadian Institutes of Health Research, 2018-2022

Principal investigators

Shannon Majowicz (University of ��ݮ��Ƶ), (University of Guelph)

University of ��ݮ��Ƶ lead researcher

Irene Lambraki

Collaborating institutions

University of ��ݮ��Ƶ (Shannon Majowicz, Irene Lambraki, Melanie Cousins, Sara Abdelrahman), University of Guelph (Jane Parmley),��Royal Swedish Academy of Sciences and the Stockholm Resilience Centre (, Tiscar Graells, Patrik Henriksson, Max Troell), University of Geneva (, Anaïs Leger), University of Geneva Hospitals and Faculty of Medicine (), Public Health Agency of Canada (Carolee Carson), WorldFish (Patrik Henriksson).

External site

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Project summary

Antimicrobial resistance (AMR) is a threat to human, animal and environmental health globally.��This project examines what is needed to build system resilience to tackle AMR in selected high-income and low-middle income contexts. In contribution to the��AMResilience��project, the Foodborne Disease Epidemiology Group is using causal loop diagrams (CLDs) and��scenario analyses to determine what actions will help to build social and ecological capacity and readiness to tackle AMR now and in the future.

Applying a One Health approach, complex adaptive system lens, and social-ecological system resilience theory to AMR, this research will quantify CLDs of AMR in the Europe and Southeast Asian food system context that are developed by diverse stakeholders in participatory workshops.��CLDs are models that help visualize how different factors in a system are related. CLDs are used to create visual models of the underlying causal structure (factors, connections, and feedbacks) that generates and spreads AMR within One Health systems in a high-income region (Europe) and a low-middle income region (Southeast Asia).��Using these CLDs, the long-term impacts of selected interventions on AMR will be explored under alternate future scenarios (e.g., climate change) via simulation modelling and participatory workshops with traditional and non-traditional stakeholders.

This mixed-methods research is being done in conjunction with international partners on the AMResilience project as part of the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR). Learn more about coordinated efforts of the .

Peer-reviewed publications

Wernli, D., Jørgensen, P.S., Parmley, E.J.,��Majowicz, S.E.,��Lambraki, I., Carson, C.A.,��Cousins, M., Graells, T., Henriksson, P.J., Léger, A., Harbarth, S. The Lancet Planetary Health, 2023, 7(7): e630-e637.

Cousins M., Parmley E.J., Greer A.L., Neiterman E., Lambraki I.A., Graells T., Léger A., Henriksson P.J.G., Troell M., Wernli D., Søgaard Jørgensen P., Carson C.A., Majowicz S.E. PLoS One, 2023, 18(8):e0290464. doi: 10.1371/journal.pone.0290464. PMID: 37616319; PMCID: PMC10449168.

Lambraki, I.A.,��Chadag, M.V.,��Cousins, M.,��Graells, T., Léger, A., Henriksson, P.J.G., Troell, M.F., Harbarth, S., Wernli, D., Jørgensen, P.S., Carson, C.A., Parmley, E.J.,��Majowicz, S.E.��Frontiers in Microbiology, 2023, 13: p.992507.

Lambraki, I., Cousins, M., Graells, T., Léger, A., Abdelrahman, S., Desbois, P., Gallagher, R., Staaf Larsson, B., Mattson, B., Henriksson, P., Troell, M., Jørgensen, P.S., Wernli, D., Carson, C.A., Parmley, E.J., & Majowicz, S.E.��. Frontiers in Public Health, 2022, 10:831097. doi: 10.3389/fpubh.2022.831097.

Graells, T., Lambraki, I.A., Cousins, M., Léger, A., Lillepold, K., Henriksson, P.J.G., Troell, M., Carson, C.A., Parmley, E.J., Majowicz, S.E., Wernli, D., Søgaard Jørgensen, P.�� Antibiotics, 2022, 11, 639. https:// doi.org/10.3390/antibiotics11050639

Lambraki, I.A.,��Cousins, M., Graells, T., Léger, A., Henriksson, P., Harbarth, S., Troell, M., Wernli, D., Søgaard Jørgensen, P., Desbois, A.P., Carson, C.A., Parmley, E.J.,��Majowicz, S.E.�� PLOS ONE, 2022, 17(2), e0263914.

Lambraki, I.A., Majowicz, S.E., Parmley, E.J., Wernli, D., Léger, A., Graells, T., Cousins, M., Harbarth, S., Carson, C., Henriksson, P., Troell, M. . JMIR Research Protocols, 2021, 10(6):e24378.

Léger, A., Lambraki, I., Graells, T., Cousins, M., Henriksson, P., Harbarth, S., Carson, C., Majowicz, S.E., Troell, M., Parmley, E.J., Jørgensen, P.S., & Wernli, D.�� BMC Infectious Diseases, 2021, 21(1), 873. DOI: 10.1186/s12879-021-06483-z.

Léger, A., Lambraki, I., Graells, T., Cousins, M., Henriksson, P., Harbarth, S., Carson, C., Majowicz, S., Troell, M., Parmley, E.J., Jørgensen, P.S., Wernli, D. . Journal of Antimicrobial Chemotherapy, 2021, 76, 1-21.

Wernli, D., Jørgensen, P. S., Parmley, E. J., Troell, M., Majowicz, S., Harbarth, S., Léger, A., Lambraki, I., Graells, T., Henriksson, J. G., Carson, C., Cousins, M., ... Carson, C. . The Lancet Infectious Diseases, 2020, 20(12), e307-e311.

Data files

Cousins, M.��, 2022,����, Borealis, V1, UNF:6:7MNV1+/sxDeftXfWjznwkg== [fileUNF]

Cousins, M. , 2022,��, Borealis, V2

Cousins, M.��, 2022,��, Borealis, V1, UNF:6:Scmti+htcN4SQ9/sgkUwFQ== [fileUNF]

Research brief

“Factors influencing antimicrobial resistance in food systems & recommendations for long-term governance under a changing climate. Research Brief.”

����Full PDF here

Created by:��Irene Lambraki��

Cite this as:��Lambraki IA, Cousins, M, Graells T, Troell M,��Søgaard JørgensenP, Wernli D, Parmley EJ, Majowicz SE. “Factors influencing antimicrobial resistance in food systems & recommendations for long-term governance under a changing climate. Research Brief”. 2022 Mar 21. Available from:��/foodborne-disease-epidemiology-group/research/amresilience

Infographic

"A review of the evidence landscape to parameterize a One Health model of AMR��in the Swedish food system context: Using expert knowledge in the interim?"

PDF

Created by: Melanie Cousins��

Cite this as:��Cousins, M. A review of the evidence landscape to parameterize a One Health model of AMR in a Swedish food system context: Using expert knowledge in the interim? [Infogrpahic]. 2021 Oct 29. Available from:��/foodborne-disease-epidemiology-group/research/amresilience

Content created to guide participatory workshop discussions

The following work is all licensed under a . This means the material is free to be shared as long there is attribution, it is noncommericial and there are no derivatives. Read the for further information.

1) "A look at Sweden as it greets the 2050 new year”: scenario newsletter developed for participatory scenario analysis workshops in Sweden

PDF

This work is licensed under a .

Cite this as: Wysong P, Kwan X, Cousins M, Lambraki I, Carson C, Parmley J, Majowicz S. "A look at Sweden as it greets the 2050 new year”: scenario newsletter developed for participatory scenario analysis workshops in Sweden [internet]. 2020 Nov 5. Available from: /food-epi-group/sites/ca.foodborne-disease-epidemiology-group/files/uploads/files/swedenscenarionewsletter2020.pdf

2) "Malaysia suffers greatly from climate change”: scenario newsletter developed for participatory scenario analysis workshops in Malaysia

PDF

This work is licensed under a .

Cite this as: Wysong P, Kwan X, Cousins M, Lambraki I, Carson C, Parmley J, Majowicz S. "Malaysia suffers greatly from climate change”: scenario newsletter developed for participatory scenario analysis workshops in Malaysia [internet]. 2020 Nov 5. Available from: /food-epi-group/sites/ca.foodborne-disease-epidemiology-group/files/uploads/files/malaysiascenarionewsletter2020.pdf

3) "Welcome to the world in 2050": Scenario video developed for participatory scenario analysis workshops in Sweden