Qing-Bin Lu
Biography
Professor Lu’s research programs cross disciplines in physics, chemistry, environment, climate, biology and medicine, particularly focusing on femtomedicine and cancer therapy, as well as the sciences of atmospheric ozone depletion (the ozone holes) and global climate change (“global warming”).
Research Interests
Ultrafast laser spectroscopic techniques
Drug Discovery, Design and Delivery
Nano-scale and atomic-scale surface science
Climate Change and Geosciences
Biochemistry and Biophysics
Photonics
Molecular Therapeutics and Theranostics
Ozone Depletion and Climate Change
Scholarly Research
Education
1997 PhD Physics, University of Newcastle, Newcastle, New South Wales, Australia
1989 MSc Physics, The Chinese Academy of Science, Xicheng District, Beijing, China
1986 BSc Physics, Fuzhou University, Fuzhou, Fujian Province, China
Awards
2014 to 2021, University Research Chair, University of ݮƵ
2008-2013, New Investigator Award, Canadian Institute of Health Research (CIHR)
2007-2012, Early Researcher Award, Ontario's Ministry of Research and Innovation
2001-2006, Senior Research Fellowship (Phases I & II), Canadian Institute of Health Research (CIHR)
Professional Associations
2012-2023 Canadian Institutes of Health Research, Peer Review Committee, member
2008-present Member of the College of Reviewers for Canada Research Chairs program
2012-2013 Canadian Cancer Society Research Institute, Peer Review Committee, member
2012-2013 Terry Fox New Frontiers Program in Cancer, Peer Review Committee, member for Team Grant
Affiliations and Volunteer Work
Cross appointment, Department of Biology, University of ݮƵ
Cross appointment, Department of Chemistry, University of ݮƵ
Teaching*
- PHYS 359 - Statistical Mechanics
- Taught in 2023, 2025
- PHYS 380 - Molecular and Cellular Biophysics
- Taught in 2020, 2021, 2023, 2024
- PHYS 395 - Biophysics of Therapeutic Methods
- Taught in 2020, 2022, 2024
- PHYS 490 - Special topics in Physics
- Taught in 2024
- PHYS 491 - Special Topics in Life, Medical and Biophysics
- Taught in 2020
* Only courses taught in the past 5 years are displayed.
Selected/Recent Publications
QB Lu, Critical Review on Radiative Forcing and Climate Models for Global Climate Change since 1970, Atmosphere 14(8), 1232(2023) (33 pages); . Highlighted by United Nations and relevant organizations in X (Twitter) ( ), and discussed in six series reports in Climate Discussion Nexus and in a series of YouTube talks by a Canadian historian and journalist, Dr. John Robson ( ; ; ;; ; ).
QB Lu, Formulation of the cosmic ray–driven electron-induced reaction mechanism for quantitative understanding of global ozone depletion. Proc. Natl. Acad. Sci. USA (PNAS) 120, e2303048120 (1-11) (2023).
QB Lu, Response to “Comment on ‘Observation of large and all-season ozone losses over the tropics’” [AIP Adv. 12, 075006 (2022)], AIP Advances 12, 129101(2022) (17 pages). See also a recent paper by Li, Dhomse, Chipperfield et al. Quantifying stratospheric ozone trends over 1984–2020: a comparison of ordinary and regularized multivariate regression models. Atmos. Chem. Phys. 23, 13029-13047 (2023), which reported the largest ozone loss (up to -29.6% per decade) at 100 hPa (~15 km altitude) over the Tropics for the period 1984-1997.
QB Lu, Major Contribution of Halogenated Greenhouse Gases to Global Surface Temperature Change. Atmosphere 13(9), 1419(1-16) (2022).
QB Lu, Observation of Large and All-Season Ozone Losses over the Tropics, AIP Advances 12 (7), 075006 (1-12) (2022). This paper reports the first discovery of the all-season tropical ozone hole that has depth similar to that of the well-known springtime Antarctic ozone hole while its area is seven times larger. This article was chosen by the Editors of AIP Advances to publish as a Featured Article and highlighted by an American Institute of Physics (AIP) Press Release: “Discovery Reveals Large, Year-Round Ozone Hole Over Tropics” ( ).
Zhang, Q.R. and Lu, Q.B. New combination chemotherapy of cisplatin with an electron‑donating compound for treatment of multiple cancers, (Springer Nature’s) Scientific Reports 11:788(2021).
Lu, Q.B. Reaction Cycles of Halogen Species in the Immune Defense: Implications for Human Health and Diseases and the Pathology and Treatment of COVID-19. Cells 9: 1461(1-18) (2020).
Hu, Y., Honek, J., Wilson, B. and Lu, Q.B. Design, synthesis and photocytotoxicity of upconversion nanoparticles: Potential applications for near-infrared photodynamic and photothermal therapy. J Biophotonics. 2019: e201900129 (1-11).
Goetze, R.G., Buchholz, S.M., Ou, N., Zhang, Q.B., Patil, S., Schirmer, M., Singh, S.K., Ellenrieder, V., Hessmann, E., Lu, Q.B. and Neesse, A. Preclinical evaluation of1,2-Diamino-4,5-dibromobenzene in genetically engineered mouse models of pancreatic cancer. Cells 8: 563(1-14) (2019).
Luo, T., Zhang, Q.R. and Lu, Q.B. Combination of Near Infrared Light-Activated Photodynamic Therapy Mediated by Indocyanine Green with Etoposide to Treat Non-Small-Cell Lung Cancer. Cancers 9: 63(1-17) (2017).
Wang, C.R., Mahmood, J., Zhang, Q.R., Vedadi, A., Warrington, J., Ou, N., Bristow, R.G., Jaffray, D.A., and Lu, Q.B., In Vitro and In Vivo Studies of a New Class of Anticancer Molecules for Targeted Radiotherapy of Cancer. Mol. Cancer Ther. 15, pp. 640-650 (2016).
Lu, Q.B., Zhang, Q.R., Ou, N., Wang, C.R. and Warrington, J. In vitro and in vivo Studies of Non-Platinum-Based Halogenated Compounds as a New Class of Potent Antitumor Agents for Natural Targeted Chemotherapy of Cancers. EBioMedicine 2, pp. 544-553 (2015).
Lu, Q.B. Cosmic-Ray-Driven Electron-Induced Reactions of Halogenated Molecules Adsorbed on Ice Surfaces: Implications for Atmospheric Ozone Depletion and Global Climate Change. Physics Reports 487, pp. 141-167 (2010).
Wang, C.R., Nguyen, J. and Lu, Q.B. Bond Breaks of Nucleotides by Dissociative Electron Transfer of Nonequilibrium Prehydrated Electrons: A New Molecular Mechanism for Reductive DNA Damage. J. Am. Chem. Soc. 131, pp. 11320-11322 (2009).
Lu, Q.B. and Sanche, L. Effects of Cosmic Rays on Atmospheric Chlorofluorocarbon Dissociation and Ozone Depletion. Phys. Rev. Lett. 87, pp. 078501(1)-078501(4) (2001)
In The News
- June 18, 2020 UW News: "New mechanism and drugs to boost immune system, potentially treat COVID-19 discovered"
- May 12, 2015 Press release by UW: "ݮƵ researcher discovers molecules that could kill cancer cells while protecting healthy cells"
- May 31, 2013 Press release by UW: "Global warming caused by CFCs, not carbon dioxide"