BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Drupal iCal API//EN X-WR-CALNAME:Events items teaser X-WR-TIMEZONE:America/Toronto BEGIN:VTIMEZONE TZID:America/Toronto X-LIC-LOCATION:America/Toronto BEGIN:DAYLIGHT TZNAME:EDT TZOFFSETFROM:-0500 TZOFFSETTO:-0400 DTSTART:20180311T070000 END:DAYLIGHT BEGIN:STANDARD TZNAME:EST TZOFFSETFROM:-0400 TZOFFSETTO:-0500 DTSTART:20171105T060000 END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:68291efa8b998 DTSTART;TZID=America/Toronto:20181017T160000 SEQUENCE:0 TRANSP:TRANSPARENT DTEND;TZID=America/Toronto:20181017T160000 URL:/statistics-and-actuarial-science/events/david-spro tt-distinguished-lecture-speaker-dr-emery-brown SUMMARY:David Sprott Distinguished Lecture Speaker: Dr. Emery Brown\;\nAffi liation: Institute for Medical Engineering & Science CLASS:PUBLIC DESCRIPTION:Summary \n\nUNCOVERING THE MECHANISMS OF GENERAL ANESTHESIA: WH ERE NEUROSCIENCE\nMEETS STATISTICS\n\n-------------------------\n\nGeneral anesthesia is a drug-induced\, reversible condition involving\nunconsciou sness\, amnesia (loss of memory)\, analgesia (loss of pain\nsensation)\, a kinesia (immobility)\, and hemodynamic stability. I will\ndescribe a prima ry mechanism through which anesthetics create these\naltered states of aro usal. Our studies have allowed us to give a\ndetailed characterization of the neurophysiology of loss and recovery\nof consciousness​\, in the cas e of propofol\, and we have demonstrated\n​​ that the state of general anesthesia can be rapidly reversed by\nactivating specific brain circuits . The success of our research has\ndepended critically on tight coupling o f experiments\, ​statistical\nsignal processing​​ and mathematical m odeling.\n DTSTAMP:20250517T234250Z END:VEVENT END:VCALENDAR