@article {layton2005region, title = {A region-based mathematical model of the urine concentrating mechanism in the rat outer medulla. I. Formulation and base-case results}, journal = {American Journal of Physiology-Renal Physiology}, volume = {289}, number = {6}, year = {2005}, pages = {F1346{\textendash}F1366}, publisher = {American Physiological Society}, author = {Layton, Anita T and Layton, Harold E} }