@article {sadria2023adversarial, title = {Adversarial training improves model interpretability in single-cell RNA-seq analysis}, journal = {bioRxiv}, year = {2023}, pages = {2023{\textendash}05}, publisher = {Cold Spring Harbor Laboratory}, author = {Sadria, Mehrshad and Layton, Anita and Bader, Gary} } @article {abo2023can, title = {Can the clocks tick together despite the noise? Stochastic simulations and analysis}, journal = {SIAM Journal on Applied Dynamical Systems}, volume = {22}, number = {2}, year = {2023}, pages = {850{\textendash}877}, publisher = {Society for Industrial and Applied Mathematics University City, Philadelphia}, author = {Abo, St{\'e}phanie MC and Carrillo, Jos{\'e} A and Layton, Anita T} } @article {hakimi2023coupling, title = {Coupling of renal sodium and calcium transport: A modeling analysis}, journal = {bioRxiv}, year = {2023}, pages = {2023{\textendash}05}, publisher = {Cold Spring Harbor Laboratory}, author = {Hakimi, Shervin and Dutta, Pritha and Layton, Anita} } @article {hakimi2023coupling, title = {Coupling of renal sodium and calcium transport: a modeling analysis of transporter inhibition and sex differences}, journal = {American Journal of Physiology-Renal Physiology}, volume = {325}, number = {5}, year = {2023}, pages = {F536{\textendash}F551}, publisher = {American Physiological Society Rockville, MD}, author = {Hakimi, Shervin and Dutta, Pritha and Layton, Anita T} } @booklet {layton2023did, title = {Did you know how SGLT2 inhibitors protect the kidney?}, journal = {Acta Physiologica}, year = {2023}, pages = {e14011}, author = {Layton, Anita T and Vallon, Volker} } @article {stadt2023differential, title = {Differential impacts of pregnancy and lactation on maternal calcium homeostasis: a mathematical modeling analysis}, journal = {Physiology}, volume = {38}, number = {S1}, year = {2023}, pages = {5730988}, publisher = {American Physiological Society Rockville, MD}, author = {Stadt, Melissa and Alexander, Todd and Layton, Anita} } @article {stadt2023effect, title = {Effect of pregnancy and hypertension on kidney function in female rats: Modeling and functional implications}, journal = {Plos one}, volume = {18}, number = {5}, year = {2023}, pages = {e0279785}, publisher = {Public Library of Science San Francisco, CA USA}, author = {Stadt, Melissa M and West, Crystal A and Layton, Anita T} } @article {layton2023hi, title = {{\textquotedblleft}Hi, how can i help you?{\textquotedblright}: embracing artificial intelligence in kidney research}, journal = {American Journal of Physiology-Renal Physiology}, volume = {325}, number = {4}, year = {2023}, pages = {F395{\textendash}F406}, publisher = {American Physiological Society Rockville, MD}, author = {Layton, Anita T} } @article {smith2023impact, title = {Impact of angiotensin-receptor blockers on intrarenal renin-angiotensin system activity in hypertension: A PK/PD modelling study}, journal = {bioRxiv}, year = {2023}, pages = {2023{\textendash}07}, publisher = {Cold Spring Harbor Laboratory}, author = {Smith, Delaney and Layton, Anita} } @article {dutta2023influence, title = {Influence of administration time and sex on natriuretic, diuretic, and kaliuretic effects of diuretics}, journal = {American Journal of Physiology-Renal Physiology}, volume = {324}, number = {3}, year = {2023}, pages = {F274{\textendash}F286}, publisher = {American Physiological Society Rockville, MD}, author = {Dutta, Pritha and Sadria, Mehrshad and Layton, Anita T} } @article {smith2023intrarenal, title = {The intrarenal renin-angiotensin system in hypertension: insights from mathematical modelling}, journal = {Journal of Mathematical Biology}, volume = {86}, number = {4}, year = {2023}, pages = {58}, publisher = {Springer Berlin Heidelberg Berlin/Heidelberg}, author = {Smith, Delaney and Layton, Anita} } @article {saulnier2023loss, title = {Loss of Glomerular Permselectivity in Type 2 Diabetes Associates with Progression to Kidney Failure}, journal = {Diabetes}, volume = {72}, number = {11}, year = {2023}, pages = {1682{\textendash}1691}, publisher = {American Diabetes Association}, author = {Saulnier, Pierre J and Looker, Helen C and Layton, Anita and Lemley, Kevin V and Nelson, Robert G and Bjornstad, Petter} } @article {stadt2023mathematical, title = {Mathematical modeling of calcium homeostasis in female rats: An analysis of sex differences and maternal adaptations}, journal = {Journal of Theoretical Biology}, volume = {572}, year = {2023}, pages = {111583}, publisher = {Academic Press}, author = {Stadt, Melissa M and Layton, Anita T} } @article {dutta2023modeling, title = {Modeling magnesium and calcium transport along male rat kidney and the effects of diuretics}, journal = {bioRxiv}, year = {2023}, pages = {2023{\textendash}10}, publisher = {Cold Spring Harbor Laboratory}, author = {Dutta, Pritha and Layton, Anita} } @article {sadria2023multimodal, title = {A multimodal neural network that distinguishes between type 1 and type 2 diabetes in young persons using MRI and clinical data}, journal = {Physiology}, volume = {38}, number = {S1}, year = {2023}, pages = {5695980}, publisher = {American Physiological Society Rockville, MD}, author = {Sadria, Mehrshad and Bjornstad, Petter and Pottumarthi, Prasad and Lu-Ping, Li and Pyle, Laura and Vigers, Timothy and Layton, Anita} } @article {sadria2023power, title = {The Power of Two: integrating deep diffusion models and variational autoencoders for single-cell transcriptomics analysis}, journal = {bioRxiv}, year = {2023}, pages = {2023{\textendash}04}, publisher = {Cold Spring Harbor Laboratory}, author = {Sadria, Mehrshad and Layton, Anita} } @article {basu2023random, title = {A random forest in the Great Lakes: Stream nutrient concentrations across the transboundary Great Lakes Basin}, journal = {Earth{\textquoteright}s Future}, volume = {11}, number = {4}, year = {2023}, pages = {e2021EF002571}, author = {Basu, Nandita B and Dony, J and Van Meter, KJ and Johnston, Samuel J and Layton, Anita T} } @article {layton2023sex, title = {Sex and time-of-day differences in kidney oxygen consumption}, journal = {bioRxiv}, year = {2023}, pages = {2023{\textendash}04}, publisher = {Cold Spring Harbor Laboratory}, author = {Layton, Anita and Dutta, Pritha} } @article {mcdonough2023sex, title = {Sex differences in renal electrolyte transport}, journal = {Current Opinion in Nephrology and Hypertension}, volume = {10}, year = {2023}, pages = {1097}, author = {McDonough, Alicia A. and Layton and T., Anita} } @article {mcdonough2023sex, title = {Sex differences in renal transporters: assessment and functional consequences}, journal = {Nature Reviews Nephrology}, year = {2023}, pages = {1{\textendash}16}, publisher = {Nature Publishing Group UK London}, author = {McDonough, Alicia A and Harris, Autumn N and Xiong, Lingyun and Layton, Anita T} } @conference {stadt2022adaptive, title = {Adaptive Changes in GFR, Tubular Morphology and Transport in Pregnant Rat Kidneys: Modeling and Analysis}, booktitle = {2022 Virtual Joint Mathematics Meetings}, year = {2022}, month = {2022}, publisher = {AMS}, organization = {AMS}, address = {JMM 2022}, author = {Stadt, Melissa and Layton, Anita} } @article {stadt2022adaptive, title = {Adaptive changes in single-nephron GFR, tubular morphology, and transport in a pregnant rat nephron: modeling and analysis}, journal = {American Journal of Physiology-Renal Physiology}, volume = {322}, number = {2}, year = {2022}, pages = {F121{\textendash}F137}, publisher = {American Physiological Society Rockville, MD}, author = {Stadt, Melissa M and Layton, Anita T} } @article {carrillo2022can, title = {Can the clocks tick together despite the noise? Stochastic simulations and analysis}, year = {2022}, publisher = {Society for Industrial and Applied Mathematics}, author = {Carrillo, JA and Abo, SMC and Layton, Anita T} } @article {stadt2022circadian, title = {Circadian Regulation of Electrolyte and Water Transport in the Rat Kidney}, journal = {SIAM Journal on Applied Mathematics}, year = {2022}, pages = {S1{\textendash}S16}, publisher = {Society for Industrial and Applied Mathematics University City, Philadelphia}, author = {Stadt, Melissa M and Abo, St{\'e}phanie and Layton, Anita T} } @article {evans2022clinical, title = {Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study}, journal = {The Lancet Respiratory Medicine}, volume = {10}, number = {8}, year = {2022}, pages = {761{\textendash}775}, publisher = {Elsevier}, author = {Evans, Rachael Andrea and Leavy, Olivia C and Richardson, Matthew and Elneima, Omer and McAuley, Hamish JC and Shikotra, Aarti and Singapuri, Amisha and Sereno, Marco and Saunders, Ruth M and Harris, Victoria C and others} } @article {layton2022comparative, title = {A Comparative Study of Epithelial Transport in the Rat and Mouse Kidneys: Modelling and Analysis}, journal = {bioRxiv}, year = {2022}, pages = {2022{\textendash}07}, publisher = {Cold Spring Harbor Laboratory}, author = {Layton, Anita T} } @article {bell2022complete, title = {A Complete Set of Equations and Parameters for the Computational Model of Mitochondrial Function for the Proximal Convoluted Tubule and Medullary Thick Ascending Limb Cells in the Rat Kidney}, journal = {bioRxiv}, year = {2022}, pages = {2022{\textendash}01}, publisher = {Cold Spring Harbor Laboratory}, author = {Bell, T William and Layton, Anita T} } @article {layton2022complete, title = {A Complete Set of Equations for a Computational Model of Electrolyte and Water Transport along the Nephrons in a Mammalian Kidney}, journal = {bioRxiv}, year = {2022}, pages = {2022{\textendash}09}, publisher = {Cold Spring Harbor Laboratory}, author = {Layton, Anita T} } @booklet {abo2022control, title = {Control Applications for Biomedical Engineering Systems}, year = {2022}, publisher = {SIAM PUBLICATIONS 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA}, author = {Abo, St{\'e}phanie and Hakimi, Shervin and Layton, Anita T and Sadria, Mehrshad and Smith, Delaney and Stadt, Melissa and West, Chris} } @article {dutta2022determinants, title = {Determinants of natriuretic, diuretic, and kaliuretic effects of diuretics: Sex and administration time}, journal = {bioRxiv}, year = {2022}, pages = {2022{\textendash}12}, publisher = {Cold Spring Harbor Laboratory}, author = {Dutta, Pritha and Sadria, Mehrshad and Layton, Anita} } @article {leete2022determining, title = {Determining risk factors for triple whammy acute kidney injury}, journal = {Mathematical Biosciences}, volume = {347}, year = {2022}, pages = {108809}, publisher = {Elsevier}, author = {Leete, Jessica and Wang, Carolyn and L{\'o}pez-Hern{\'a}ndez, Francisco J and Layton, Anita T} } @article {sadria2022fatecode, title = {Fatecode: Cell fate regulator prediction using classification autoencoder perturbation}, journal = {bioRxiv}, year = {2022}, pages = {2022{\textendash}12}, publisher = {Cold Spring Harbor Laboratory}, author = {Sadria, Mehrshad and Layton, Anita and Goyal, Sidhartha and Bader, Gary} } @article {stadt2022your, title = {From your kidneys to your eyes: lessons from computational kidney models}, journal = {Modeling and Artificial Intelligence in Ophthalmology}, volume = {4}, number = {1}, year = {2022}, author = {Stadt, Melissa M and Layton, Anita} } @article {smith2022intrarenal, title = {Intrarenal Renin-Angiotensin System and its Role in Angiotensin II-Induced Hypertension: Insights from Computational Modelling}, journal = {The FASEB Journal}, volume = {36}, year = {2022}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Smith, Delaney and Layton, Anita} } @article {stadt2022mathematical, title = {A mathematical model of potassium homeostasis: Effect of feedforward and feedback controls}, journal = {PLOS Computational Biology}, volume = {18}, number = {12}, year = {2022}, pages = {e1010607}, publisher = {Public Library of Science San Francisco, CA USA}, author = {Stadt, Melissa M and Leete, Jessica and Devinyak, Sophia and Layton, Anita T} } @article {sadria2022mixed, title = {The mixed blessing of AMPK signaling in Cancer treatments}, journal = {BMC cancer}, volume = {22}, number = {1}, year = {2022}, pages = {1{\textendash}16}, publisher = {BioMed Central}, author = {Sadria, Mehrshad and Seo, Deokhwa and Layton, Anita T} } @article {abo2022modelling, title = {Modelling female physiology from head to toe: Impact of sex hormones, menstrual cycle, and pregnancy}, journal = {Journal of Theoretical Biology}, volume = {540}, year = {2022}, pages = {111074}, publisher = {Academic Press}, author = {Abo, St{\'e}phanie and Smith, Delaney and Stadt, Melissa and Layton, Anita} } @article {layton2022modelling, title = {Modelling Sex Differences in Circadian Regulation of Kidney Function of the Mouse}, journal = {bioRxiv}, year = {2022}, pages = {2022{\textendash}08}, publisher = {Cold Spring Harbor Laboratory}, author = {Layton, Anita T and Gumz, Michelle L} } @article {sadria2022predictive, title = {A predictive model for estimating protection against CKD and CVD with SGLT2 inhibition in patients with diabetes}, journal = {The FASEB Journal}, volume = {36}, year = {2022}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Sadria, Mehrshad and Layton, Anita} } @article {stadt2022renal, title = {Renal adaptations in gestational hypertension preserves K+ while minimizing Na+ retention}, journal = {The FASEB Journal}, volume = {36}, year = {2022}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Stadt, Melissa and Layton, Anita} } @article {stadt2022sex, title = {Sex and species differences in epithelial transport in rat and mouse kidneys: Modeling and analysis}, journal = {Frontiers in physiology}, volume = {13}, year = {2022}, pages = {991705}, publisher = {Frontiers}, author = {Stadt, Melissa Maria and Layton, Anita T} } @article {layton2022sex, title = {Sex differences in circadian regulation of kidney function of the mouse}, journal = {American Journal of Physiology-Renal Physiology}, volume = {323}, number = {6}, year = {2022}, pages = {F675{\textendash}F685}, publisher = {American Physiological Society Rockville, MD}, author = {Layton, Anita T and Gumz, Michelle L} } @article {swapnasrita2022sex, title = {Sex-specific computational models of kidney function in patients with diabetes}, journal = {Frontiers in physiology}, volume = {13}, year = {2022}, pages = {14}, publisher = {Frontiers}, author = {Swapnasrita, Sangita and Carlier, Aurelie and Layton, Anita T} } @article {layton2022understanding, title = {Understanding the dynamics of SARS-CoV-2 variants of concern in Ontario, Canada: a modeling study}, journal = {Scientific Reports}, volume = {12}, number = {1}, year = {2022}, pages = {2114}, publisher = {Nature Publishing Group UK London}, author = {Layton, Anita T and Sadria, Mehrshad} } @article {sadria2021aging, title = {Aging affects circadian clock and metabolism and modulates timing of medication}, journal = {Iscience}, volume = {24}, number = {4}, year = {2021}, publisher = {Elsevier}, author = {Sadria, Mehrshad and Layton, Anita T} } @article {sadria2021computational, title = {A computational model for cell energy balance and metabolism}, year = {2021}, author = {Sadria, Mehrshad and Layton, Anita T} } @article {hu2021computational, title = {A computational model of kidney function in a patient with diabetes}, journal = {International journal of molecular sciences}, volume = {22}, number = {11}, year = {2021}, pages = {5819}, publisher = {MDPI}, author = {Hu, Rui and Layton, Anita} } @article {patterson2021computing, title = {Computing viscous flow along a 2D open channel using the immersed interface method}, journal = {Engineering Reports}, volume = {3}, number = {5}, year = {2021}, pages = {e12334}, author = {Patterson, Sarah E and Layton, Anita T} } @article {patterson2021computing, title = {Computing Viscous Flow Along a 3D Open Tube Using the Immerse Interface Method}, journal = {arXiv preprint arXiv:2112.12892}, year = {2021}, author = {Patterson, Sarah E and Layton, Anita T} } @booklet {layton2021deep, title = {Deep Learning for Medical Decision Support Systems}, year = {2021}, publisher = {SIAM PUBLICATIONS 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA}, author = {Layton, Anita T} } @booklet {abo2021dynamics, title = {The Dynamics of Biological Systems}, year = {2021}, publisher = {SIAM PUBLICATIONS 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA}, author = {Abo, St{\'e}phanie and Layton, Anita T} } @article {casanova2021furosemide, title = {The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats}, journal = {Translational Research}, volume = {231}, year = {2021}, pages = {76{\textendash}91}, publisher = {Mosby}, author = {Casanova, Alfredo G and Fuentes-Calvo, Isabel and Hern{\'a}ndez-S{\'a}nchez, Mar{\'\i}a T and Quintero, Miguel and Toral, Paula and Caballero, Mar{\'\i}a T and Mart{\'\i}nez-Salgado, Carlos and Morales, Ana I and Layton, Anita T and Eleno, N{\'e}lida and others} } @article {docherty2021haemodynamic, title = {Haemodynamic frailty{\textendash}A risk factor for acute kidney injury in the elderly}, journal = {Ageing Research Reviews}, volume = {70}, year = {2021}, pages = {101408}, publisher = {Elsevier}, author = {Docherty, Neil G and Delles, Christian and D{\textquoteright}Haese, Patrick and Layton, Anita T and Mart{\'\i}nez-Salgado, Carlos and Vervaet, Benjamin A and L{\'o}pez-Hern{\'a}ndez, Francisco J} } @article {layton2021his, title = {His and her mathematical models of physiological systems}, journal = {Mathematical Biosciences}, volume = {338}, year = {2021}, pages = {108642}, publisher = {Elsevier}, author = {Layton, Anita T} } @article {ahmed2021impact, title = {Impact of sex and pathophysiology on optimal drug choice in hypertensive rats: quantitative insights for precision medicine}, journal = {Iscience}, volume = {24}, number = {4}, year = {2021}, publisher = {Elsevier}, author = {Ahmed, Sameed and Sullivan, Jennifer C and Layton, Anita T} } @article {sadria2021interactions, title = {Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism}, journal = {Cell Communication and Signaling}, volume = {19}, number = {1}, year = {2021}, pages = {1{\textendash}17}, publisher = {BioMed Central}, author = {Sadria, Mehrshad and Layton, Anita T} } @article {bell2021mathematical, title = {A Mathematical Model of Mitochondria in Proximal Tubule and Thick Ascending Limb Cells}, journal = {bioRxiv}, year = {2021}, pages = {2021{\textendash}12}, publisher = {Cold Spring Harbor Laboratory}, author = {Bell, William and Layton, Anita T} } @booklet {layton2021mining, title = {Mining of Massive Datasets.}, year = {2021}, publisher = {SIAM PUBLICATIONS 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA}, author = {Layton, Anita and Sadria, Mehrshad} } @article {bell2021model, title = {A Model of Mitochondria in the Rat Hepatocyte}, journal = {bioRxiv}, year = {2021}, pages = {2021{\textendash}12}, publisher = {Cold Spring Harbor Laboratory}, author = {Bell, William and Layton, Anita T} } @article {abo2021modeling, title = {Modeling the circadian regulation of the immune system: Sexually dimorphic effects of shift work}, journal = {PLoS computational biology}, volume = {17}, number = {3}, year = {2021}, pages = {e1008514}, publisher = {Public Library of Science}, author = {Abo, St{\'e}phanie MC and Layton, Anita T} } @article {sadria2021modeling, title = {Modeling within-host SARS-CoV-2 infection dynamics and potential treatments}, journal = {Viruses}, volume = {13}, number = {6}, year = {2021}, pages = {1141}, publisher = {MDPI}, author = {Sadria, Mehrshad and Layton, Anita T} } @article {hu2021sex, title = {Sex differences in solute and water handling in the human kidney: Modeling and functional implications}, journal = {IScience}, volume = {24}, number = {6}, year = {2021}, publisher = {Elsevier}, author = {Hu, Rui and McDonough, Alicia A and Layton, Anita T} } @article {layton2021sex, title = {Sex-specific Effects of SGLT2 Inhibition in a Kidney with Reduced Nephron Number: Modeling and Analysis}, journal = {bioRxiv}, year = {2021}, pages = {2021{\textendash}12}, publisher = {Cold Spring Harbor Laboratory}, author = {Layton, Anita T} } @conference {abo2021sex, title = {Sex-Specific Effects of Shiftwork-Mediated Disruptions of Circadian Rhythms on the Inflammatory Response}, booktitle = {2021 Joint Mathematics Meetings}, year = {2021}, publisher = {AMS}, organization = {AMS}, address = {JMM 2021}, author = {Abo, St{\'e}phanie and Layton, Anita} } @article {sadria2020ageing, title = {Ageing signalling pathways: Quantifying the effects of protein interactions}, journal = {The FASEB Journal}, volume = {34}, number = {S1}, year = {2020}, pages = {1{\textendash}1}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Sadria, Mehrshad and Layton, Anita} } @inbook {layton2020diabetes, title = {Diabetes implications on kidneys}, booktitle = {Diabetes Systems Biology: Quantitative methods for understanding beta-cell dynamics and function}, year = {2020}, pages = {10{\textendash}1}, publisher = {IOP Publishing Bristol, UK}, organization = {IOP Publishing Bristol, UK}, author = {Layton, Anita T and Hu, Rui} } @booklet {sadria2020first, title = {A First Course in Systems Biology.}, year = {2020}, publisher = {SIAM PUBLICATIONS 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA}, author = {Sadria, Mehrshad and Layton, Anita T} } @booklet {layton2020mathematical, title = {Mathematical Modelling and Biomechanics of the Brain}, year = {2020}, publisher = {SIAM PUBLICATIONS 3600 UNIV CITY SCIENCE CENTER, PHILADELPHIA, PA 19104-2688 USA}, author = {Layton, Anita T} } @article {edwards2020model, title = {A model of mitochondrial O2 consumption and ATP generation in rat proximal tubule cells}, journal = {American Journal of Physiology-Renal Physiology}, volume = {318}, number = {1}, year = {2020}, pages = {F248{\textendash}F259}, publisher = {American Physiological Society Bethesda, MD}, author = {Edwards, Aur{\'e}lie and Palm, Fredrik and Layton, Anita T} } @article {prieto2020pathophysiological, title = {Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury}, journal = {Laboratory Investigation}, volume = {100}, number = {11}, year = {2020}, pages = {1455{\textendash}1464}, publisher = {Nature Publishing Group US New York}, author = {Prieto-Garc{\'\i}a, Laura and Vicente-Vicente, Laura and Blanco-Gozalo, V{\'\i}ctor and Hidalgo-Thomas, Omar and Garc{\'\i}a-Mac{\'\i}as, Mar{\'\i}a C and Kurtz, Armin and Layton, Anita T and Sanz, Ana B and Morales, Ana I and Mart{\'\i}nez-Salgado, Carlos and others} } @article {hu2020sex, title = {Sex differences in solute transport along the nephrons: effects of Na+ transport inhibition}, journal = {American Journal of Physiology-Renal Physiology}, volume = {319}, number = {3}, year = {2020}, pages = {F487{\textendash}F505}, publisher = {American Physiological Society Bethesda, MD}, author = {Hu, Rui and McDonough, Alicia A and Layton, Anita T} } @article {ahmed2020sex, title = {Sex-specific computational models for blood pressure regulation in the rat}, journal = {American Journal of Physiology-Renal Physiology}, volume = {318}, number = {4}, year = {2020}, pages = {F888{\textendash}F900}, publisher = {American Physiological Society Bethesda, MD}, author = {Ahmed, Sameed and Layton, Anita T} } @article {sadria2020use, title = {Use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers during the COVID-19 pandemic: a modeling analysis}, journal = {PLoS Computational Biology}, volume = {16}, number = {10}, year = {2020}, pages = {e1008235}, publisher = {Public Library of Science San Francisco, CA USA}, author = {Sadria, Mehrshad and Layton, Anita T} } @article {layton2019computational, title = {A computational model of epithelial solute and water transport along a human nephron}, journal = {PLoS computational biology}, volume = {15}, number = {2}, year = {2019}, pages = {e1006108}, publisher = {Public Library of Science}, author = {Layton, Anita T and Layton, Harold E} } @article {leete2019determining, title = {Determining Risk Factors for Triple Whammy AKI using Computational Models of Long-Term Blood Pressure Regulation}, journal = {The FASEB Journal}, volume = {33}, number = {S1}, year = {2019}, pages = {758{\textendash}5}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Leete, Jessica and Ahmed, Sameed and Lopez Hernandez, Francisco J and Layton, Anita} } @article {guidoboni2019electrochemical, title = {Electrochemical characterization of ciliary epithelium physiology: a theoretical approach}, journal = {Investigative Ophthalmology \& Visual Science}, volume = {60}, number = {9}, year = {2019}, pages = {3202{\textendash}3202}, publisher = {The Association for Research in Vision and Ophthalmology}, author = {Guidoboni, Giovanna and Bonifazi, Giulio and Sacco, Riccardo and Layton, Anita and Olson, Sarah D and Hallare, Maila C Brucal and Siesky, Brent A and Bruttini, Carlo and Vercellin, Alice Chandra Verticchio and Harris, Alon} } @article {hu2019functional, title = {Functional Implications of Sexual Dimorphism of Transporter Patterns along the Rat Nephron}, journal = {The FASEB Journal}, volume = {33}, number = {S1}, year = {2019}, pages = {864{\textendash}1}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Hu, Rui and McDonough, Alicia A and Layton, Anita} } @article {hu2019functional, title = {Functional implications of the sex differences in transporter abundance along the rat nephron: modeling and analysis}, journal = {American Journal of Physiology-Renal Physiology}, volume = {317}, number = {6}, year = {2019}, pages = {F1462{\textendash}F1474}, publisher = {American Physiological Society Bethesda, MD}, author = {Hu, Rui and McDonough, Alicia A and Layton, Anita T} } @article {fattah2019kidneys, title = {How do kidneys adapt to a deficit or loss in nephron number?}, journal = {Physiology}, volume = {34}, number = {3}, year = {2019}, pages = {189{\textendash}197}, publisher = {American Physiological Society Bethesda, MD}, author = {Fattah, Hadi and Layton, Anita and Vallon, Volker} } @article {akhter2019impact, title = {Impact of shifting epithelial Na+ transport on renal medullary oxygen tension: Modeling and analysis}, journal = {The FASEB Journal}, volume = {33}, number = {S1}, year = {2019}, pages = {748{\textendash}1}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Akhter, Tahmina and Layton, Anita} } @article {ahmed2019integrative, title = {Integrative Cardiovascular Physiology and Pathophysiology: Understanding sex differences in long-term blood pressure regulation: insights from experimental studies and computational modeling}, journal = {American Journal of Physiology-Heart and Circulatory Physiology}, volume = {316}, number = {5}, year = {2019}, pages = {H1113}, publisher = {American Physiological Society}, author = {Ahmed, Sameed and Hu, Rui and Leete, Jessica and Layton, Anita T} } @article {layton2019multiscale, title = {Multiscale models of kidney function and diseases}, journal = {Current Opinion in Biomedical Engineering}, volume = {11}, year = {2019}, pages = {1{\textendash}8}, publisher = {Elsevier}, author = {Layton, Anita T} } @article {sadria2019network, title = {Network centrality analysis of eye-gaze data in autism spectrum disorder}, journal = {Computers in biology and medicine}, volume = {111}, year = {2019}, pages = {103332}, publisher = {Pergamon}, author = {Sadria, Mehrshad and Karimi, Soroush and Layton, Anita T} } @article {layton2019optimizing, title = {Optimizing SGLT inhibitor treatment for diabetes with chronic kidney diseases}, journal = {Biological Cybernetics}, volume = {113}, number = {1-2}, year = {2019}, pages = {139{\textendash}148}, publisher = {Springer Berlin Heidelberg Berlin/Heidelberg}, author = {Layton, Anita T} } @article {layton2019recent, title = {Recent advances in renal epithelial transport}, journal = {American Journal of Physiology-Renal Physiology}, volume = {316}, number = {2}, year = {2019}, pages = {F274{\textendash}F276}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {layton2019recent, title = {Recent advances in sex differences in kidney function}, journal = {American Journal of Physiology-Renal Physiology}, volume = {316}, number = {2}, year = {2019}, pages = {F328{\textendash}F331}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Sullivan, Jennifer C} } @article {ahmed2019sex, title = {Sex-specific Computational Models for Blood Pressure Regulation in the Rat}, journal = {The FASEB Journal}, volume = {33}, number = {S1}, year = {2019}, pages = {758{\textendash}6}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Ahmed, Sameed and Leete, Jessica and Hernandez, Francisco Lopez and Layton, Anita} } @article {leete2019sex, title = {Sex-specific long-term blood pressure regulation: Modeling and analysis}, journal = {Computers in biology and medicine}, volume = {104}, year = {2019}, pages = {139{\textendash}148}, publisher = {Pergamon}, author = {Leete, Jessica and Layton, Anita T} } @article {layton2019solute, title = {Solute and water transport along an inner medullary collecting duct undergoing peristaltic contractions}, journal = {American Journal of Physiology-Renal Physiology}, volume = {317}, number = {3}, year = {2019}, pages = {F735{\textendash}F742}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {ahmed2019understanding, title = {Understanding sex differences in long-term blood pressure regulation: insights from experimental studies and computational modeling}, journal = {American Journal of Physiology-Heart and Circulatory Physiology}, volume = {316}, number = {5}, year = {2019}, pages = {H1113{\textendash}H1123}, publisher = {American Physiological Society Bethesda, MD}, author = {Ahmed, Sameed and Hu, Rui and Leete, Jessica and Layton, Anita T} } @article {layton2018cardiovascular, title = {Cardiovascular benefits of SGLT2 inhibition in diabetes and chronic kidney diseases}, journal = {Acta physiologica (Oxford, England)}, volume = {222}, number = {4}, year = {2018}, pages = {e13050}, publisher = {NIH Public Access}, author = {Layton, Anita T and Vallon, Volker} } @article {li2018functional, title = {Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis}, journal = {American Journal of Physiology-Renal Physiology}, volume = {315}, number = {3}, year = {2018}, pages = {F692{\textendash}F700}, publisher = {American Physiological Society Bethesda, MD}, author = {Li, Qianyi and McDonough, Alicia A and Layton, Harold E and Layton, Anita T} } @article {layton2018handbook, title = {Handbook of Numerical Methods for Hy-perbolic Problems: Basic and Fundamen}, journal = {SIAM Review Vol. 60, Issue 3 (September 2018)}, volume = {60}, number = {3}, year = {2018}, pages = {768}, author = {Layton, Anita T} } @article {leete2018his, title = {His and Her Computational Models of Long-term Blood Pressure Regulation}, journal = {The FASEB Journal}, volume = {32}, year = {2018}, pages = {714{\textendash}5}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Leete, Jessica and Layton, Anita} } @article {ciocanel2018maria, title = {Maria-Veronica Ciocanel}, journal = {Dynamical Systems}, volume = {17}, year = {2018}, pages = {2855{\textendash}2881}, author = {Ciocanel, MV and Jung, P and Brown, A and Panaggio, MJ and Lazarus, L and Topaz, CM and Xu, B and Sandstede, B and Jeschonek, SP and Mowry, KL and others} } @article {leete2018modeling, title = {Modeling sex differences in the renin angiotensin system and the efficacy of antihypertensive therapies}, journal = {Computers \& chemical engineering}, volume = {112}, year = {2018}, pages = {253{\textendash}264}, publisher = {Pergamon}, author = {Leete, Jessica and Gurley, Susan and Layton, Anita T} } @article {ciocanel2018multicellular, title = {A multicellular vascular model of the renal myogenic response}, journal = {Processes}, volume = {6}, number = {7}, year = {2018}, pages = {89}, publisher = {MDPI}, author = {Ciocanel, Maria-Veronica and Stepien, Tracy L and Sgouralis, Ioannis and Layton, Anita T} } @article {wei2018predicted, title = {Predicted effect of circadian clock modulation of NHE3 of a proximal tubule cell on sodium transport}, journal = {American Journal of Physiology-Renal Physiology}, volume = {315}, number = {3}, year = {2018}, pages = {F665{\textendash}F676}, publisher = {American Physiological Society Bethesda, MD}, author = {Wei, Ning and Gumz, Michelle L and Layton, Anita T} } @article {layton2018renal, title = {Renal potassium handling in rats with subtotal nephrectomy: modeling and analysis}, journal = {American Journal of Physiology-Renal Physiology}, volume = {314}, number = {4}, year = {2018}, pages = {F643{\textendash}F657}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Vallon, Volker} } @article {layton2018renal, title = {Renal tubular solute transport and oxygen consumption: insights from computational models}, journal = {Current Opinion in Nephrology and Hypertension}, volume = {27}, number = {5}, year = {2018}, pages = {384{\textendash}389}, publisher = {LWW}, author = {Layton, Anita T and Vallon, Volker} } @article {layton2018sglt2, title = {SGLT2 inhibition in a kidney with reduced nephron number: modeling and analysis of solute transport and metabolism}, journal = {American Journal of Physiology-Renal Physiology}, volume = {314}, number = {5}, year = {2018}, pages = {F969{\textendash}F984}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Vallon, Volker} } @article {layton2018sweet, title = {Sweet success? SGLT2 inhibitors and diabetes}, journal = {American Journal of Physiology-Renal Physiology}, volume = {314}, number = {6}, year = {2018}, pages = {F1034{\textendash}F1035}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {wei2018theoretical, title = {Theoretical assessment of the Ca 2+ oscillations in the afferent arteriole smooth muscle cell of the rat kidney}, journal = {International Journal of Biomathematics}, volume = {11}, number = {03}, year = {2018}, pages = {1850043}, publisher = {World Scientific Publishing Company}, author = {Wei, Ning and Layton, Anita T} } @article {layton2017adaptive, title = {Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis}, journal = {American Journal of Physiology-Renal Physiology}, volume = {313}, number = {2}, year = {2017}, pages = {F199{\textendash}F209}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Vallon, Volker} } @article {layton2017archive, title = {Archive of all online content}, journal = {American Journal of Physiology-Renal Physiology}, volume = {313}, number = {5}, year = {2017}, pages = {F1178{\textendash}F1178}, author = {Layton, AT and Pannabecker, TL and Dantzler, WH and Layton, HE} } @article {edwards2017cell, title = {Cell volume regulation in the proximal tubule of rat kidney: proximal tubule cell volume regulation}, journal = {Bulletin of mathematical biology}, volume = {79}, number = {11}, year = {2017}, pages = {2512{\textendash}2533}, publisher = {Springer US New York}, author = {Edwards, Aur{\'e}lie and Layton, Anita T} } @article {jiang2017generation, title = {Generation and phenotypic analysis of mice lacking all urea transporters}, journal = {Kidney international}, volume = {91}, number = {2}, year = {2017}, pages = {338{\textendash}351}, publisher = {Elsevier}, author = {Jiang, Tao and Li, Yingjie and Layton, Anita T and Wang, Weiling and Sun, Yi and Li, Min and Zhou, Hong and Yang, Baoxue} } @article {burt2017intra, title = {Intra-Target Microdosing (ITM): a novel drug development approach aimed at enabling safer and earlier translation of biological insights into human testing}, journal = {Clinical and Translational Science}, volume = {10}, number = {5}, year = {2017}, pages = {337}, publisher = {Wiley-Blackwell}, author = {Burt, T and Noveck, RJ and MacLeod, DB and Layton, AT and Rowland, M and Lappin, Graham} } @conference {layton2017introduction, title = {Introduction to Mathematical Modeling of Blood Flow Control in the Kidney}, booktitle = {Women in Mathematical Biology: Research Collaboration Workshop, NIMBioS, Knoxville, June 2015}, year = {2017}, pages = {63{\textendash}73}, publisher = {Springer International Publishing}, organization = {Springer International Publishing}, author = {Layton, Anita T and Edwards, Aur{\'e}lie} } @conference {ciocanel2017modeling, title = {Modeling autoregulation of the afferent arteriole of the rat kidney}, booktitle = {Women in Mathematical Biology: Research Collaboration Workshop, NIMBioS, Knoxville, June 2015}, year = {2017}, pages = {75{\textendash}100}, publisher = {Springer International Publishing}, organization = {Springer International Publishing}, author = {Ciocanel, Maria-Veronica and Stepien, Tracy L and Edwards, Aur{\'e}lie and Layton, Anita T} } @conference {sgouralis2017modeling, title = {Modeling blood flow and oxygenation in a diabetic rat kidney}, booktitle = {Women in Mathematical Biology: Research Collaboration Workshop, NIMBioS, Knoxville, June 2015}, year = {2017}, pages = {101{\textendash}113}, publisher = {Springer International Publishing}, organization = {Springer International Publishing}, author = {Sgouralis, Ioannis and Layton, Anita T} } @article {chen2017modeling, title = {Modeling glucose metabolism and lactate production in the kidney}, journal = {Mathematical biosciences}, volume = {289}, year = {2017}, pages = {116{\textendash}129}, publisher = {Elsevier}, author = {Chen, Ying and Fry, Brendan C and Layton, Anita T} } @article {layton2017modeling, title = {Modeling the Effects of Functional Adaptation to Reduction in Renal Mass}, journal = {The FASEB Journal}, volume = {31}, year = {2017}, pages = {716{\textendash}2}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Layton, Anita and Edwards, Aur{\'e}lie and Vallon, Volker} } @article {layton2017new, title = {A new microscope for the kidney: mathematics}, journal = {American Journal of Physiology-Renal Physiology}, volume = {312}, number = {4}, year = {2017}, pages = {F671{\textendash}F672}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {sgouralis2017renal, title = {Renal medullary and urinary oxygen tension during cardiopulmonary bypass in the rat}, journal = {Mathematical medicine and biology: a journal of the IMA}, volume = {34}, number = {3}, year = {2017}, pages = {313{\textendash}333}, publisher = {Oxford University Press}, author = {Sgouralis, Ioannis and Evans, Roger G and Layton, Anita T} } @article {chen2017sex, title = {Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting nitric oxide bioavailability}, journal = {American Journal of Physiology-Renal Physiology}, volume = {313}, number = {2}, year = {2017}, pages = {F174{\textendash}F183}, publisher = {American Physiological Society Bethesda, MD}, author = {Chen, Ying and Sullivan, Jennifer C and Edwards, Aur{\'e}lie and Layton, Anita T} } @conference {layton2017tracking, title = {Tracking the Distribution of a Solute Bolus in the Rat Kidney}, booktitle = {Women in Mathematical Biology: Research Collaboration Workshop, NIMBioS, Knoxville, June 2015}, year = {2017}, pages = {115{\textendash}136}, publisher = {Springer International Publishing}, organization = {Springer International Publishing}, author = {Layton, Anita T} } @article {layton2017two, title = {Two modes for concentrating urine in rat inner medulla (vol 287, pg F816, 2004)}, journal = {AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY}, volume = {313}, number = {5}, year = {2017}, pages = {F1178{\textendash}F1178}, publisher = {AMER PHYSIOLOGICAL SOC 9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA}, author = {Layton, AT and Pannabecker, TL and Dantzler, WH and Layton, HE} } @booklet {layton2017women, title = {Women in mathematical biology: research collaboration workshop, Nimbios, Knoxville, June 2015}, year = {2017}, publisher = {Springer}, author = {Layton, Anita T and Miller, Laura A} } @article {sgouralis2016bladder, title = {Bladder urine oxygen tension for assessing renal medullary oxygenation in rabbits: experimental and modeling studies}, journal = {American Journal of Physiology-Regulatory, Integrative and Comparative Physiology}, volume = {311}, number = {3}, year = {2016}, pages = {R532{\textendash}R544}, publisher = {American Physiological Society Bethesda, MD}, author = {Sgouralis, Ioannis and Kett, Michelle M and Ow, Connie PC and Abdelkader, Amany and Layton, Anita T and Gardiner, Bruce S and Smith, David W and Lankadeva, Yugeesh R and Evans, Roger G} } @article {layton2016computational, title = {A computational model for simulating solute transport and oxygen consumption along the nephrons}, journal = {American Journal of Physiology-Renal Physiology}, volume = {311}, number = {6}, year = {2016}, pages = {F1378{\textendash}F1390}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Vallon, Volker and Edwards, Aur{\'e}lie} } @article {sgouralis2016conduction, title = {Conduction of feedback-mediated signal in a computational model of coupled nephrons}, journal = {Mathematical Medicine and Biology: a Journal of the IMA}, volume = {33}, number = {1}, year = {2016}, pages = {87{\textendash}106}, publisher = {Oxford University Press}, author = {Sgouralis, Ioannis and Layton, Anita T} } @article {xie2016dynamic, title = {Dynamic contrast-enhanced quantitative susceptibility mapping with ultrashort echo time MRI for evaluating renal function}, journal = {American Journal of Physiology-Renal Physiology}, volume = {310}, number = {2}, year = {2016}, pages = {F174{\textendash}F182}, publisher = {American Physiological Society Bethesda, MD}, author = {Xie, Luke and Layton, Anita T and Wang, Nian and Larson, Peder EZ and Zhang, Jeff L and Lee, Vivian S and Liu, Chunlei and Johnson, G Allan} } @article {layton2016effect, title = {Effect of SGLT Inhibition on Medullary Oxygen Consumption: A Multi-Nephron Model of the Rat Kidney}, journal = {The FASEB Journal}, volume = {30}, year = {2016}, pages = {740{\textendash}2}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Layton, Anita and Vallon, Volker and Edwards, Aur{\'e}lie} } @article {nganguia2016electrohydrodynamics, title = {Electrohydrodynamics of a viscous drop with inertia}, journal = {Physical Review E}, volume = {93}, number = {5}, year = {2016}, pages = {053114}, publisher = {American Physical Society}, author = {Nganguia, H and Young, Y-N and Layton, AT and Lai, M-C and Hu, W-F} } @article {herschlag2016fluid, title = {Fluid extraction across pumping and permeable walls in the viscous limit}, journal = {Physics of Fluids}, volume = {28}, number = {4}, year = {2016}, publisher = {AIP Publishing}, author = {Herschlag, G and Liu, J-G and Layton, AT} } @article {fry2016impact, title = {Impact of nitric-oxide-mediated vasodilation and oxidative stress on renal medullary oxygenation: a modeling study}, journal = {American Journal of Physiology-Renal Physiology}, volume = {310}, number = {3}, year = {2016}, pages = {F237{\textendash}F247}, publisher = {American Physiological Society Bethesda, MD}, author = {Fry, Brendan C and Edwards, Aur{\'e}lie and Layton, Anita T} } @article {sgouralis2016internephron, title = {Internephron Coupling Increases the Efficiency of Dynamic Autoregulation}, journal = {The FASEB Journal}, volume = {30}, year = {2016}, pages = {739{\textendash}6}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Sgouralis, Ioannis and Layton, Anita} } @article {chen2016modeling, title = {Modeling glucose metabolism in the kidney}, journal = {Bulletin of mathematical biology}, volume = {78}, year = {2016}, pages = {1318{\textendash}1336}, publisher = {Springer US}, author = {Chen, Ying and Fry, Brendan C and Layton, Anita T} } @article {liu2016modeling, title = {Modeling the effects of positive and negative feedback in kidney blood flow control}, journal = {Mathematical biosciences}, volume = {276}, year = {2016}, pages = {8{\textendash}18}, publisher = {Elsevier}, author = {Liu, Runjing and Layton, Anita T} } @article {layton2016predicted, title = {Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron}, journal = {American Journal of Physiology-Renal Physiology}, volume = {310}, number = {11}, year = {2016}, pages = {F1269{\textendash}F1283}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Vallon, Volker and Edwards, Aur{\'e}lie} } @article {layton2016recent, title = {Recent advances in renal hypoxia: Insights from bench experiments and computer simulations}, journal = {American Journal of Physiology-Renal Physiology}, volume = {311}, number = {1}, year = {2016}, pages = {F162{\textendash}F165}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {chen2016sex, title = {Sex Differences in Hypertension: A Modeling Study}, journal = {The FASEB Journal}, volume = {30}, year = {2016}, pages = {959{\textendash}1}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Chen, Ying and Edwards, Aur{\'e}lie and Sullivan, Jennifer and Layton, Anita} } @article {layton2016solute, title = {Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors}, journal = {American Journal of Physiology-Renal Physiology}, volume = {311}, number = {6}, year = {2016}, pages = {F1217{\textendash}F1229}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Laghmani, Kamel and Vallon, Volker and Edwards, Aur{\'e}lie} } @article {sgouralis2016transfer, title = {Transfer function analysis of dynamic blood flow control in the rat kidney}, journal = {Bulletin of mathematical biology}, volume = {78}, number = {5}, year = {2016}, pages = {923{\textendash}960}, publisher = {Springer US}, author = {Sgouralis, Ioannis and Maroulas, Vasileios and Layton, Anita T} } @article {versypt2015bifurcation, title = {Bifurcation study of blood flow control in the kidney}, journal = {Mathematical biosciences}, volume = {263}, year = {2015}, pages = {169{\textendash}179}, publisher = {Elsevier}, author = {Versypt, Ashlee N Ford and Makrides, Elizabeth and Arciero, Julia C and Ellwein, Laura and Layton, Anita T} } @article {herschlag2015exact, title = {An exact solution for stokes flow in a channel with arbitrarily large wall permeability}, journal = {SIAM Journal on Applied Mathematics}, volume = {75}, number = {5}, year = {2015}, pages = {2246{\textendash}2267}, publisher = {Society for Industrial and Applied Mathematics}, author = {Herschlag, G and Liu, J-G and Layton, Anita T} } @article {nganguia2015immersed, title = {An immersed interface method for axisymmetric electrohydrodynamic simulations in Stokes flow}, journal = {Communications in Computational Physics}, volume = {18}, number = {2}, year = {2015}, pages = {429{\textendash}449}, publisher = {Cambridge University Press}, author = {Nganguia, H and Young, Y-N and Layton, AT and Hu, W-F and Lai, M-C} } @article {fry2015impacts, title = {Impacts of nitric oxide and superoxide on renal medullary oxygen transport and urine concentration}, journal = {American Journal of Physiology-Renal Physiology}, volume = {308}, number = {9}, year = {2015}, pages = {F967{\textendash}F980}, publisher = {American Physiological Society Bethesda, MD}, author = {Fry, Brendan C and Edwards, Aur{\'e}lie and Layton, Anita T} } @article {baird2015implications, title = {Implications of Increased Renal Venous Pressure for Renal Hemodynamic and Reabsorptive Function Studied by a Mathematical Model of the Kidney}, journal = {The FASEB Journal}, volume = {29}, year = {2015}, pages = {808{\textendash}19}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Baird, Austin and Braam, Branko and Layton, Anita} } @article {burt2015intraarterial, title = {Intraarterial microdosing: a novel drug development approach, proof-of-concept PET study in rats}, journal = {Journal of Nuclear Medicine}, volume = {56}, number = {11}, year = {2015}, pages = {1793{\textendash}1799}, publisher = {Society of Nuclear Medicine}, author = {Burt, Tal and Rouse, Douglas C and Lee, Kihak and Wu, Huali and Layton, Anita T and Hawk, Thomas C and Weitzel, Douglas H and Chin, Bennett B and Cohen-Wolkowiez, Michael and Chow, Shein-Chung and others} } @article {burt2015intra, title = {Intra-arterial microdosing (IAM), a novel drug development approach, proof of concept in rats}, journal = {Clinical Therapeutics}, volume = {37}, number = {8}, year = {2015}, pages = {e40{\textendash}e41}, publisher = {Elsevier}, author = {Burt, T and Wu, H and Layton, AT and Rouse, DC and Chin, BB and Hawk, TC and Weitzel, DH and Cohen-Wolkowiez, M and Chow, S and Noveck, RJ} } @article {sgouralis2015mathematical, title = {Mathematical modeling of renal hemodynamics in physiology and pathophysiology}, journal = {Mathematical biosciences}, volume = {264}, year = {2015}, pages = {8{\textendash}20}, publisher = {Elsevier}, author = {Sgouralis, Ioannis and Layton, Anita T} } @conference {arciero2015modeling, title = {Modeling blood flow control in the kidney}, booktitle = {Applications of dynamical systems in biology and medicine}, year = {2015}, pages = {55{\textendash}73}, publisher = {Springer New York}, organization = {Springer New York}, author = {Arciero, Julia and Ellwein, Laura and Versypt, Ashlee N Ford and Makrides, Elizabeth and Layton, Anita T} } @article {layton2015modeling, title = {Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition}, journal = {American Journal of Physiology-Renal Physiology}, volume = {308}, number = {12}, year = {2015}, pages = {F1343{\textendash}F1357}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Vallon, Volker and Edwards, Aur{\'e}lie} } @article {fry2015nitric, title = {Nitric Oxide and Superoxide Significantly Affect Medullary Oxygenation and Urinary Output}, journal = {The FASEB Journal}, volume = {29}, year = {2015}, pages = {963{\textendash}1}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Fry, Brendan and Edwards, Aur{\'e}lie and Layton, Anita} } @article {herschlag2015optimal, title = {Optimal reservoir conditions for fluid extraction through permeable walls in the viscous limit}, journal = {arXiv preprint arXiv:1511.01469}, year = {2015}, author = {Herschlag, Gregory and Liu, Jian-Guo and Layton, Anita T} } @article {layton2015predicted, title = {Predicted effects of nitric oxide and superoxide on the vasoactivity of the afferent arteriole}, journal = {American Journal of Physiology-Renal Physiology}, volume = {309}, number = {8}, year = {2015}, pages = {F708{\textendash}F719}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Edwards, Aur{\'e}lie} } @article {layton2015recent, title = {Recent advances in renal hemodynamics: insights from bench experiments and computer simulations}, journal = {American Journal of Physiology-Renal Physiology}, volume = {308}, number = {9}, year = {2015}, pages = {F951{\textendash}F955}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {sgouralis2015renal, title = {Renal hemodynamics, function, and oxygenation during cardiac surgery performed on cardiopulmonary bypass: a modeling study}, journal = {Physiological reports}, volume = {3}, number = {1}, year = {2015}, pages = {e12260}, author = {Sgouralis, Ioannis and Evans, Roger G and Gardiner, Bruce S and Smith, Julian A and Fry, Brendan C and Layton, Anita T} } @article {edwards2015sglt2, title = {SGLT2 Inhibition Is Predicted to Increase NaCl Delivery to the Medullary Thick Ascending Limb But Not to Significantly Elevate Its Oxygen Consumption}, journal = {The FASEB Journal}, volume = {29}, year = {2015}, pages = {959{\textendash}3}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Edwards, Aur{\'e}lie and Vallon, Volker and Layton, Anita} } @article {sgouralis2015urinary, title = {Urinary PO2 as a biomarker for medullary hypoxia}, journal = {The FASEB Journal}, volume = {29}, year = {2015}, pages = {963{\textendash}6}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Sgouralis, Ioannis and Evans, Roger and Gardiner, Bruce and Layton, Anita} } @booklet {layton2014biological, title = {Biological Fluid Dynamics: Modeling, Computations, and Applications}, year = {2014}, publisher = {American Mathematical Society}, author = {Layton, Anita T and Olson, Sarah D} } @article {edwards2014calcium, title = {Calcium dynamics underlying the myogenic response of the renal afferent arteriole}, journal = {American Journal of Physiology-Renal Physiology}, volume = {306}, number = {1}, year = {2014}, pages = {F34{\textendash}F48}, publisher = {American Physiological Society}, author = {Edwards, Aur{\'e}lie and Layton, Anita T} } @article {li2014computing, title = {Computing viscous flow in an elastic tube}, journal = {Numerical Mathematics: Theory, Methods and Applications}, volume = {7}, number = {4}, year = {2014}, pages = {555{\textendash}574}, publisher = {Cambridge University Press}, author = {Li, Yi and Sgouralis, Ioannis and Layton, Anita T} } @article {sgouralis2014contribution, title = {Contribution of hemodilution to renal hypoxia following cardiopulmonary bypass surgery (890.12)}, journal = {The FASEB Journal}, volume = {28}, year = {2014}, pages = {890{\textendash}12}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Sgouralis, Ioannis and Evans, Roger and Gardiner, Bruce and Layton, Anita} } @article {layton2014counter, title = {Counter-Current Exchange Across Vasa Recta}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {63{\textendash}83}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {moss2014dominant, title = {Dominant factors that govern pressure natriuresis in diuresis and antidiuresis: a mathematical model}, journal = {American Journal of Physiology-Renal Physiology}, volume = {306}, number = {9}, year = {2014}, pages = {F952{\textendash}F969}, publisher = {American Physiological Society Bethesda, MD}, author = {Moss, Robert and Layton, Anita T} } @article {edwards2014effects, title = {Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study}, journal = {American Journal of Physiology-Renal Physiology}, volume = {307}, number = {2}, year = {2014}, pages = {F137{\textendash}F146}, publisher = {American Physiological Society Bethesda, MD}, author = {Edwards, Aur{\'e}lie and Castrop, Hayo and Laghmani, Kamel and Vallon, Volker and Layton, Anita T} } @article {layton2014electrophysiology, title = {Electrophysiology of Renal Vascular Smooth Muscle Cells}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {107{\textendash}140}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @conference {herschlag2014exact, title = {An exact solution for Stokes flow in an infinite channel with permeable walls}, booktitle = {APS Division of Fluid Dynamics Meeting Abstracts}, year = {2014}, pages = {D15{\textendash}006}, author = {Herschlag, Gregory and Liu, Jian-Guo and Layton, Anita} } @article {ryu2014feedback, title = {Feedback-mediated dynamics in a model of coupled nephrons with compliant short loop of Henle}, journal = {Biological Fluid Dynamics: Modeling, Computations, and Applications}, volume = {628}, year = {2014}, pages = {209}, publisher = {American Mathematical Soc.}, author = {Ryu, Hwayeon and Layton, Anita T} } @article {layton2014glomerular, title = {Glomerular Filtration}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {7{\textendash}41}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @conference {nganguia2014immersed, title = {Immersed Interface Method for Drop Electrohydrodynamic}, booktitle = {APS Division of Fluid Dynamics Meeting Abstracts}, year = {2014}, pages = {H13{\textendash}006}, author = {Nganguia, Herve and Young, Yuan-Nan and Layton, Anita and Hu, Wei-Fan and Lai, Ming-Chih} } @article {fry2014impact, title = {Impact of renal medullary three-dimensional architecture on oxygen transport}, journal = {American Journal of Physiology-Renal Physiology}, volume = {307}, number = {3}, year = {2014}, pages = {F263{\textendash}F272}, publisher = {American Physiological Society Bethesda, MD}, author = {Fry, Brendan C and Edwards, Aur{\'e}lie and Sgouralis, Ioannis and Layton, Anita T} } @article {layton2014impacts, title = {Impacts of Facilitated Urea Transporters on the Urine-Concentrating Mechanism in the Rat Kidney}, journal = {Biological Fluid Dynamics: Modeling, Computations, and Applications}, volume = {628}, year = {2014}, pages = {191}, publisher = {American Mathematical Soc.}, author = {Layton, Anita T} } @article {moss2014impacts, title = {Impacts of UT-A2 inhibition on urine composition: a mathematical model (1137.8)}, journal = {The FASEB Journal}, volume = {28}, year = {2014}, pages = {1137{\textendash}8}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Moss, Rob and Layton, Anita} } @article {layton2014introduction, title = {Introduction: Basics of Kidney Physiology}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {1{\textendash}5}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @booklet {layton2014mathematical, title = {Mathematical modeling in renal physiology}, year = {2014}, publisher = {Springer Berlin}, author = {Layton, Anita T and Edwards, Aur{\'e}lie} } @article {layton2014mathematical, title = {Mathematical modeling of urea transport in the kidney}, journal = {Urea Transporters}, year = {2014}, pages = {31{\textendash}43}, publisher = {Springer Netherlands}, author = {Layton, Anita T} } @article {olson2014motion, title = {Motion of filaments with planar and helical bending waves in a viscous fluid}, journal = {Biological Fluid Dynamics: Modeling, Computation, and Applications, AMS Contemp. Math. Series, Layton A, Olson S (eds). AMS: Providence, RI}, year = {2014}, pages = {109{\textendash}128}, author = {Olson, Sarah D and Layton, A and Olson, S} } @article {fry2014oxygen, title = {Oxygen transport in a cross section of the rat inner medulla: Impact of heterogeneous distribution of nephrons and vessels}, journal = {Mathematical biosciences}, volume = {258}, year = {2014}, pages = {68{\textendash}76}, publisher = {Elsevier}, author = {Fry, Brendan C and Layton, Anita T} } @article {olson2014simulating, title = {Simulating biofluid-structure interactions with an immersed boundary framework{\textendash}a review}, journal = {Biological Fluid Dynamics: Modeling, Computations, and Applications}, volume = {628}, year = {2014}, pages = {1}, publisher = {American Mathematical Soc.}, author = {Olson, Sarah D and Layton, Anita T} } @article {layton2014solutions, title = {Solutions to Problem Sets}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {185{\textendash}218}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {fry2014structural, title = {Structural organization of the renal medulla has a significant impact on oxygen distribution (890.11)}, journal = {The FASEB Journal}, volume = {28}, year = {2014}, pages = {890{\textendash}11}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Fry, Brendan and Layton, Anita} } @article {pannabecker2014targeted, title = {Targeted delivery of solutes and oxygen in the renal medulla: role of microvessel architecture}, journal = {American Journal of Physiology-Renal Physiology}, volume = {307}, number = {6}, year = {2014}, pages = {F649{\textendash}F655}, publisher = {American Physiological Society Bethesda, MD}, author = {Pannabecker, Thomas L and Layton, Anita T} } @article {sgouralis2014theoretical, title = {Theoretical assessment of renal autoregulatory mechanisms}, journal = {American Journal of Physiology-Renal Physiology}, volume = {306}, number = {11}, year = {2014}, pages = {F1357{\textendash}F1371}, publisher = {American Physiological Society Bethesda, MD}, author = {Sgouralis, Ioannis and Layton, Anita T} } @article {layton2014transport, title = {Transport across tubular epithelia}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {155{\textendash}183}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {ryu2014tubular, title = {Tubular fluid flow and distal NaCl delivery mediated by tubuloglomerular feedback in the rat kidney}, journal = {Journal of mathematical biology}, volume = {68}, year = {2014}, pages = {1023{\textendash}1049}, publisher = {Springer Berlin Heidelberg}, author = {Ryu, Hwayeon and Layton, Anita T} } @article {layton2014tubuloglomerular, title = {Tubuloglomerular Feedback}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {85{\textendash}106}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {layton2014urine, title = {Urine Concentration}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {43{\textendash}61}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {dantzler2014urine, title = {Urine-concentrating mechanism in the inner medulla: function of the thin limbs of the loops of Henle}, journal = {Clinical journal of the American Society of Nephrology: CJASN}, volume = {9}, number = {10}, year = {2014}, pages = {1781}, publisher = {American Society of Nephrology}, author = {Dantzler, William H and Layton, Anita T and Layton, Harold E and Pannabecker, Thomas L} } @article {layton2014vasomotion, title = {Vasomotion and Myogenic Response of the Afferent Arteriole}, journal = {Mathematical Modeling in Renal Physiology}, year = {2014}, pages = {141{\textendash}154}, publisher = {Springer Berlin Heidelberg}, author = {Layton, Anita T and Edwards, Aur{\'e}lie and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {sgouralis2013control, title = {Control and modulation of fluid flow in the rat kidney}, journal = {Bulletin of mathematical biology}, volume = {75}, year = {2013}, pages = {2551{\textendash}2574}, publisher = {Springer US}, author = {Sgouralis, Ioannis and Layton, Anita T} } @conference {haer2013duplication, title = {DUPLICATION OF THE UREA TRANSPORTER B GENE (KIDD BLOOD GROUP) IN A KINDRED WITH FAMILIAL AZOTEMIA}, booktitle = {VOX SANGUINIS}, volume = {105}, year = {2013}, pages = {30{\textendash}31}, publisher = {WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}, organization = {WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ USA}, author = {Haer-Wigman, L and Linthorst, GE and Sands, JM and Klein, JD and Thai, TL and Verhoeven, AJ and van Zwieten, R and Folman, C and Jansweijer, MC and Knegt, LC and others} } @article {ryu2013effect, title = {Effect of tubular inhomogeneities on feedback-mediated dynamics of a model of a thick ascending limb}, journal = {Mathematical Medicine and Biology: a Journal of the IMA}, volume = {30}, number = {3}, year = {2013}, pages = {191{\textendash}212}, publisher = {Oxford University Press}, author = {Ryu, Hwayeon and Layton, Anita T} } @article {nieves2013fluid, title = {Fluid dilution and efficiency of Na+ transport in a mathematical model of a thick ascending limb cell}, journal = {American Journal of Physiology-Renal Physiology}, volume = {304}, number = {6}, year = {2013}, pages = {F634{\textendash}F652}, publisher = {American Physiological Society Bethesda, MD}, author = {Nieves-Gonz{\'a}lez, Aniel and Clausen, Chris and Marcano, Mariano and Layton, Anita T and Layton, Harold E and Moore, Leon C} } @article {li2013hybrid, title = {A hybrid immersed interface method for driven Stokes flow in an elastic tube}, journal = {Numerical Mathematics: Theory, Methods and Applications}, volume = {6}, number = {4}, year = {2013}, pages = {600{\textendash}616}, publisher = {Cambridge University Press}, author = {Li, Yi and Williams, Sarah A and Layton, Anita T} } @article {layton2013impacts, title = {Impacts of active urea secretion into pars recta on urine concentration and urea excretion rate}, journal = {Physiological reports}, volume = {1}, number = {3}, year = {2013}, author = {Layton, Anita T and Bankir, Lise} } @article {layton2013mathematical, title = {Mathematical modeling of kidney transport}, journal = {Wiley Interdisciplinary Reviews: Systems Biology and Medicine}, volume = {5}, number = {5}, year = {2013}, pages = {557{\textendash}573}, publisher = {John Wiley \& Sons, Inc. Hoboken, USA}, author = {Layton, Anita T} } @booklet {moss2013modeling, title = {Modeling the effects of medullary blood flow regulation on pressure natriuresis}, year = {2013}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Moss, Robert and Layton, Anita} } @booklet {sgouralis2013nephrovascular, title = {Nephrovascular interactions in a mathematical model of rat renal autoregulation}, year = {2013}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Sgouralis, Ioannis and Layton, Anita} } @article {leiderman2013regularization, title = {A regularization method for the numerical solution of periodic Stokes flow}, journal = {Journal of Computational Physics}, volume = {236}, year = {2013}, pages = {187{\textendash}202}, publisher = {Elsevier}, author = {Leiderman, Karin and Bouzarth, Elizabeth L and Cortez, Ricardo and Layton, Anita T} } @article {nieves2013transport, title = {Transport efficiency and workload distribution in a mathematical model of the thick ascending limb}, journal = {American Journal of Physiology-Renal Physiology}, volume = {304}, number = {6}, year = {2013}, pages = {F653{\textendash}F664}, publisher = {American Physiological Society Bethesda, MD}, author = {Nieves-Gonz{\'a}lez, Aniel and Clausen, Chris and Layton, Anita T and Layton, Harold E and Moore, Leon C} } @article {li2012accurate, title = {Accurate computation of Stokes flow driven by an open immersed interface}, journal = {Journal of Computational Physics}, volume = {231}, number = {15}, year = {2012}, pages = {5195{\textendash}5215}, publisher = {Elsevier}, author = {Li, Yi and Layton, Anita T} } @article {sgouralis2012autoregulation, title = {Autoregulation and conduction of vasomotor responses in a mathematical model of the rat afferent arteriole}, journal = {American Journal of Physiology-Renal Physiology}, volume = {303}, number = {2}, year = {2012}, pages = {F229{\textendash}F239}, publisher = {American Physiological Society Bethesda, MD}, author = {Sgouralis, Ioannis and Layton, Anita T} } @article {ryu2012hwayeon, title = {HWAYEON RYU}, journal = {Biomed Eng}, volume = {28}, number = {3}, year = {2012}, pages = {369{\textendash}380}, author = {Ryu, H and Layton, AT and by Tubuloglomerular, Distal NaCl Delivery Mediated and others} } @article {edwards2012impact, title = {Impact of nitric oxide-mediated vasodilation on outer medullary NaCl transport and oxygenation}, journal = {American Journal of Physiology-Renal Physiology}, volume = {303}, number = {7}, year = {2012}, pages = {F907{\textendash}F917}, publisher = {American Physiological Society Bethesda, MD}, author = {Edwards, Aur{\'e}lie and Layton, Anita T} } @booklet {sgouralis2012interactions, title = {Interactions between Tubuloglomerular Feedback and the Myogenic Mechanism of the Afferent Arteriole}, year = {2012}, publisher = {Federation of American Societies for Experimental Biology}, author = {Sgouralis, Ioannis and Layton, Anita T} } @booklet {layton2012interface, title = {Interface methods for biological and biomedical problems}, journal = {International Journal for Numerical Methods in Biomedical Engineering}, volume = {28}, number = {3}, year = {2012}, pages = {289{\textendash}290}, publisher = {John Wiley \& Sons, Ltd Chichester, UK}, author = {Layton, Anita T and Wei, Guowei} } @article {layton2012isolated, title = {Isolated interstitial nodal spaces may facilitate preferential solute and fluid mixing in the rat renal inner medulla}, journal = {American Journal of Physiology-Renal Physiology}, volume = {302}, number = {7}, year = {2012}, pages = {F830{\textendash}F839}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Gilbert, Rebecca L and Pannabecker, Thomas L} } @article {savage2012mechanistic, title = {Mechanistic mathematical model of polarity in yeast}, journal = {Molecular biology of the cell}, volume = {23}, number = {10}, year = {2012}, pages = {1998{\textendash}2013}, publisher = {The American Society for Cell Biology}, author = {Savage, Natasha S and Layton, Anita T and Lew, Daniel J} } @article {layton2012modeling, title = {Modeling transport and flow regulatory mechanisms of the kidney}, journal = {International Scholarly Research Notices}, volume = {2012}, year = {2012}, publisher = {Hindawi}, author = {Layton, Anita T} } @article {hou2012numerical, title = {Numerical methods for fluid-structure interaction{\textemdash}a review}, journal = {Communications in Computational Physics}, volume = {12}, number = {2}, year = {2012}, pages = {337{\textendash}377}, publisher = {Cambridge University Press}, author = {Hou, Gene and Wang, Jin and Layton, Anita} } @article {layton2012partially, title = {A partially implicit hybrid method for computing interface motion in Stokes flow}, journal = {Discrete Contin. Dyn. Syst. Ser. B}, volume = {27}, year = {2012}, pages = {1139{\textendash}1153}, author = {Layton, Anita T and Beale, J Thomas} } @booklet {witelski2012preface, title = {PREFACE: SPECIAL ISSUE ON FLUID DYNAMICS, ANALYSIS AND NUMERICS}, journal = {DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B}, volume = {17}, number = {4}, year = {2012}, pages = {I{\textendash}II}, publisher = {AMER INST MATHEMATICAL SCIENCES PO BOX 2604, SPRINGFIELD, MO 65801-2604 USA}, author = {Witelski, Thomas P and Ambrose, David M and Bertozzi, Andrea and Layton, Anita T and Li, Zhilin and Minion, Michael L} } @booklet {gilbert2012role, title = {Role of interstitial nodal spaces in the urine concentrating mechanism of the rat kidney}, year = {2012}, publisher = {Federation of American Societies for Experimental Biology}, author = {Gilbert, Rebecca L and Pannabecker, Thomas L and Layton, Anita T} } @article {layton2012signal, title = {Signal transduction in a compliant short loop of Henle}, journal = {International journal for numerical methods in biomedical engineering}, volume = {28}, number = {3}, year = {2012}, pages = {369{\textendash}383}, publisher = {John Wiley \& Sons, Ltd Chichester, UK}, author = {Layton, Anita T and Pham, Philip and Ryu, Hwayeon} } @article {layton2012signal, title = {Signal transduction in a compliant thick ascending limb}, journal = {American Journal of Physiology-Renal Physiology}, volume = {302}, number = {9}, year = {2012}, pages = {F1188{\textendash}F1202}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Moore, Leon C and Layton, Harold E} } @booklet {layton2012special, title = {Special Issue on Fluid Motion Driven by Immersed Structures Preface}, journal = {COMMUNICATIONS IN COMPUTATIONAL PHYSICS}, volume = {12}, number = {2}, year = {2012}, pages = {I{\textendash}III}, publisher = {GLOBAL SCIENCE PRESS ROOM 3208, CENTRAL PLAZA, 18 HARBOUR RD, WANCHAI, HONG {\textellipsis}}, author = {Layton, Anita and Stockie, John and Li, Zhilin and Huang, Huaxiong} } @booklet {ryu2012tubular, title = {Tubular Fluid Oscillations Mediated by Tubuloglomerular Feedback in a Short Loop of Henle}, year = {2012}, publisher = {Federation of American Societies for Experimental Biology}, author = {Ryu, Hwayeon and Layton, Anita T} } @article {layton2012urine, title = {Urine concentrating mechanism: impact of vascular and tubular architecture and a proposed descending limb urea-Na+ cotransporter}, journal = {American Journal of Physiology-Renal Physiology}, volume = {302}, number = {5}, year = {2012}, pages = {F591{\textendash}F605}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Dantzler, William H and Pannabecker, Thomas L} } @booklet {pannabecker2012urine, title = {Urine Concentrating Mechanism: Impact of Vascular and Tubular Architecture and a Proposed Descending Limb Urea-Na Cotransporter}, year = {2012}, publisher = {Federation of American Societies for Experimental Biology}, author = {Pannabecker, Thomas L and Dantzler, William H and Layton, Anita T} } @inbook {layton2012velocity, title = {A velocity decomposition approach for solving the immersed interface problem with Dirichlet boundary conditions}, booktitle = {Natural Locomotion in Fluids and on Surfaces: Swimming, Flying, and Sliding}, year = {2012}, pages = {263{\textendash}269}, publisher = {Springer New York New York, NY}, organization = {Springer New York New York, NY}, author = {Layton, Anita T} } @article {layton2011countercurrent, title = {Countercurrent multiplication may not explain the axial osmolality gradient in the outer medulla of the rat kidney}, journal = {American Journal of Physiology-Renal Physiology}, volume = {301}, number = {5}, year = {2011}, pages = {F1047{\textendash}F1056}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Layton, Harold E} } @booklet {nieves2011dynamical, title = {Dynamical Properties of the Thick Ascending Limb (TAL): A Modeling Study}, year = {2011}, publisher = {Federation of American Societies for Experimental Biology}, author = {Nieves-Gonz{\'a}lez, Aniel and Clausen, Chris and Layton, Harold E and Layton, Anita T and Moore, Leon C} } @booklet {nieves2011efficiency, title = {Efficiency of sodium transport in a model of the Thick Ascending Limb (TAL)}, year = {2011}, publisher = {Federation of American Societies for Experimental Biology}, author = {Nieves-Gonz{\'a}lez, Aniel and Clausen, Chris and Marcano, Mariano and Layton, Harold E and Layton, Anita T and Moore, Leon C} } @article {layton2011feedback, title = {Feedback-mediated dynamics in a model of coupled nephrons with compliant thick ascending limbs}, journal = {Mathematical biosciences}, volume = {230}, number = {2}, year = {2011}, pages = {115{\textendash}127}, publisher = {Elsevier}, author = {Layton, Anita T and Bowen, Matthew and Wen, Amy and Layton, Harold E} } @booklet {pannabecker2011isolated, title = {Isolated interstitial nodal spaces facilitate preferential solute and fluid mixing}, year = {2011}, publisher = {Federation of American Societies for Experimental Biology}, author = {Pannabecker, Thomas L and Layton, Anita T} } @article {chen2011mathematical, title = {A mathematical model of the myogenic response to systolic pressure in the afferent arteriole}, journal = {American Journal of Physiology-Renal Physiology}, volume = {300}, number = {3}, year = {2011}, pages = {F669{\textendash}F681}, publisher = {American Physiological Society Bethesda, MD}, author = {Chen, Jing and Sgouralis, Ioannis and Moore, Leon C and Layton, Harold E and Layton, Anita T} } @article {layton2011mathematical, title = {A mathematical model of the urine concentrating mechanism in the rat renal medulla. I. Formulation and base-case results}, journal = {American Journal of Physiology-Renal Physiology}, volume = {300}, number = {2}, year = {2011}, pages = {F356{\textendash}F371}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {layton2011mathematical, title = {A mathematical model of the urine concentrating mechanism in the rat renal medulla. II. Functional implications of three-dimensional architecture}, journal = {American Journal of Physiology-Renal Physiology}, volume = {300}, number = {2}, year = {2011}, pages = {F372{\textendash}F384}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T} } @article {bouzarth2011modeling, title = {Modeling a semi-flexible filament in cellular Stokes flow using regularized Stokeslets}, journal = {International Journal for Numerical Methods in Biomedical Engineering}, volume = {27}, number = {12}, year = {2011}, pages = {2021{\textendash}2034}, publisher = {John Wiley \& Sons, Ltd Chichester, UK}, author = {Bouzarth, Elizabeth L and Layton, Anita T and Young, Yuan-Nan} } @article {layton2011modeling, title = {Modeling vesicle traffic reveals unexpected consequences for Cdc42p-mediated polarity establishment}, journal = {Current Biology}, volume = {21}, number = {3}, year = {2011}, pages = {184{\textendash}194}, publisher = {Elsevier}, author = {Layton, Anita T and Savage, Natasha S and Howell, Audrey S and Carroll, Susheela Y and Drubin, David G and Lew, Daniel J} } @article {edwards2011modulation, title = {Modulation of outer medullary NaCl transport and oxygenation by nitric oxide and superoxide}, journal = {American Journal of Physiology-Renal Physiology}, volume = {301}, number = {5}, year = {2011}, pages = {F979{\textendash}F996}, publisher = {American Physiological Society Bethesda, MD}, author = {Edwards, Aur{\'e}lie and Layton, Anita T} } @booklet {layton2011propagation, title = {Propagation of vasoconstrictive responses in a mathematical model of the rat afferent arteriole}, year = {2011}, publisher = {Federation of American Societies for Experimental Biology}, author = {Layton, Anita T and Sgouralis, Ioannis and Layton, Harold and Moore, Leon} } @article {lei2011role, title = {Role of thin descending limb urea transport in renal urea handling and the urine concentrating mechanism}, journal = {American Journal of Physiology-Renal Physiology}, volume = {301}, number = {6}, year = {2011}, pages = {F1251{\textendash}F1259}, publisher = {American Physiological Society Bethesda, MD}, author = {Lei, Tianluo and Zhou, Lei and Layton, Anita T and Zhou, Hong and Zhao, Xuejian and Bankir, Lise and Yang, Baoxue} } @booklet {layton2011role, title = {Role of UTB Urea Transporters in the Urine Concentrating Mechanism of the Rat Kidney}, year = {2011}, publisher = {Federation of American Societies for Experimental Biology}, author = {Layton, Anita T} } @article {dantzler2011urine, title = {Urine concentrating mechanism in the inner medulla of the mammalian kidney: role of three-dimensional architecture}, journal = {Acta physiologica}, volume = {202}, number = {3}, year = {2011}, pages = {361{\textendash}378}, publisher = {Blackwell Publishing Ltd Oxford, UK}, author = {Dantzler, WH and Pannabecker, TL and Layton, AT and Layton, HE} } @article {chen2010effects, title = {Effects of pH and medullary blood flow on oxygen transport and sodium reabsorption in the rat outer medulla}, journal = {American Journal of Physiology-Renal Physiology}, volume = {298}, number = {6}, year = {2010}, pages = {F1369{\textendash}F1383}, publisher = {American Physiological Society Bethesda, MD}, author = {Chen, Jing and Edwards, Aur{\'e}lie and Layton, Anita T} } @booklet {nieves2010efficiency, title = {Efficiency of sodium transport in the thick ascending limb}, year = {2010}, publisher = {Federation of American Societies for Experimental Biology}, author = {Nieves-Gonz{\'a}lez, Aniel and Moore, Leon C and Clausen, Chris and Marcano, Mariano and Layton, Harold E and Layton, Anita T} } @article {hallen2010expanding, title = {Expanding the scope of quantitative FRAP analysis}, journal = {Journal of Theoretical Biology}, volume = {262}, number = {2}, year = {2010}, pages = {295{\textendash}305}, publisher = {Academic Press}, author = {Hallen, Mark A and Layton, Anita T} } @article {layton2010feedback, title = {Feedback-mediated dynamics in a model of a compliant thick ascending limb}, journal = {Mathematical biosciences}, volume = {228}, number = {2}, year = {2010}, pages = {185{\textendash}194}, publisher = {Elsevier}, author = {Layton, Anita T} } @article {layton2010functional, title = {Functional implications of the three-dimensional architecture of the rat renal inner medulla}, journal = {American Journal of Physiology-Renal Physiology}, volume = {298}, number = {4}, year = {2010}, pages = {F973{\textendash}F987}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Pannabecker, Thomas L and Dantzler, William H and Layton, Harold E} } @article {layton2010hyperfiltration, title = {Hyperfiltration and inner stripe hypertrophy may explain findings by Gamble and coworkers}, journal = {American Journal of Physiology-Renal Physiology}, volume = {298}, number = {4}, year = {2010}, pages = {F962{\textendash}F972}, publisher = {American Physiological Society Bethesda, MD}, author = {Layton, Anita T and Pannabecker, Thomas L and Dantzler, William H and Layton, Harold E} } @article {layton2010mathematical, title = {A mathematical model of the afferent arteriolar smooth muscle cell}, journal = {The FASEB Journal}, volume = {24}, year = {2010}, pages = {1059{\textendash}27}, publisher = {Federation of American Societies for Experimental Biology}, author = {Layton, Harold E and Chen, Jing and Moore, Leon C and Layton, Anita T} } @article {marcano2010maximum, title = {Maximum urine concentrating capability in a mathematical model of the inner medulla of the rat kidney}, journal = {Bulletin of mathematical biology}, volume = {72}, year = {2010}, pages = {314{\textendash}339}, publisher = {Springer-Verlag}, author = {Marcano, Mariano and Layton, Anita T and Layton, Harold E} } @article {wang2010new, title = {New numerical methods for Burgers{\textquoteright} equation based on semi-Lagrangian and modified equation approaches}, journal = {Applied numerical mathematics}, volume = {60}, number = {6}, year = {2010}, pages = {645{\textendash}657}, publisher = {North-Holland}, author = {Wang, Jin and Layton, Anita} } @article {edwards2010nitric, title = {Nitric oxide and superoxide transport in a cross section of the rat outer medulla. II. Reciprocal interactions and tubulovascular cross talk}, journal = {American Journal of Physiology-Renal Physiology}, volume = {299}, number = {3}, year = {2010}, pages = {F634{\textendash}F647}, publisher = {American Physiological Society Bethesda, MD}, author = {Edwards, Aur{\'e}lie and Layton, Anita T} } @article {edwards2010nitric, title = {Nitric oxide and superoxide transport in a cross section of the rat outer medulla. I. Effects of low medullary oxygen tension}, journal = {American Journal of Physiology-Renal Physiology}, volume = {299}, number = {3}, year = {2010}, pages = {F616{\textendash}F633}, publisher = {American Physiological Society Bethesda, MD}, author = {Edwards, Aur{\'e}lie and Layton, Anita T} } @article {loreto2010optimization, title = {An optimization study of a mathematical model of the urine concentrating mechanism of the rat kidney}, journal = {Mathematical biosciences}, volume = {223}, number = {1}, year = {2010}, pages = {66{\textendash}78}, publisher = {Elsevier}, author = {Loreto, Milagros and Layton, Anita T} } @article {layton2010tubuloglomerular, title = {Tubuloglomerular feedback signal transduction in a short loop of Henle}, journal = {Bulletin of mathematical biology}, volume = {72}, year = {2010}, pages = {34{\textendash}62}, publisher = {Springer-Verlag}, author = {Layton, Anita T and Edwards, Aur{\'e}lie} } @article {layton2009drosophila, title = {Drosophila morphogenesis: tissue force laws and the modeling of dorsal closure}, journal = {HFSP journal}, volume = {3}, number = {6}, year = {2009}, pages = {441{\textendash}460}, publisher = {Taylor \& Francis}, author = {Layton, Anita T and Toyama, Yusuke and Yang, Guo-Qiang and Edwards, Glenn S and Kiehart, Daniel P and Venakides, Stephanos} } @article {layton2009efficiency, title = {On the efficiency of spectral deferred correction methods for time-dependent partial differential equations}, journal = {Applied numerical mathematics}, volume = {59}, number = {7}, year = {2009}, pages = {1629{\textendash}1643}, publisher = {North-Holland}, author = {Layton, Anita T} } @article {edwards2009impact, title = {Impact of Rat Outer Medullary Architecture on Oxygen Distribution}, journal = {The FASEB Journal}, volume = {23}, year = {2009}, pages = {970{\textendash}12}, publisher = {Federation of American Societies for Experimental Biology}, author = {Edwards, Aur{\'e}lie and Chen, Jing and Layton, Anita T} } @article {robel2009lorenz, title = {The Lorenz Model}, year = {2009}, author = {Robel, Alexander and Layton, A} } @article {layton2009mammalian, title = {The mammalian urine concentrating mechanism: hypotheses and uncertainties}, journal = {Physiology}, volume = {24}, number = {4}, year = {2009}, pages = {250{\textendash}256}, publisher = {American Physiological Society}, author = {Layton, Anita T and Layton, Harold E and Dantzler, William H and Pannabecker, Thomas L} } @article {chen2009mathematical, title = {A mathematical model of O2 transport in the rat outer medulla. I. Model formulation and baseline results}, journal = {American Journal of Physiology-Renal Physiology}, volume = {297}, number = {2}, year = {2009}, pages = {F517{\textendash}F536}, publisher = {American Physiological Society}, author = {Chen, Jing and Layton, Anita T and Edwards, Aur{\'e}lie} } @article {chen2009mathematical, title = {A mathematical model of O2 transport in the rat outer medulla. II. Impact of outer medullary architecture}, journal = {American Journal of Physiology-Renal Physiology}, volume = {297}, number = {2}, year = {2009}, pages = {F537{\textendash}F548}, publisher = {American Physiological Society}, author = {Chen, Jing and Edwards, Aur{\'e}lie and Layton, Anita T} } @article {layton2009multistable, title = {Multistable dynamics mediated by tubuloglomerular feedback in a model of coupled nephrons}, journal = {Bulletin of mathematical biology}, volume = {71}, year = {2009}, pages = {515{\textendash}555}, publisher = {Springer-Verlag}, author = {Layton, Anita T and Moore, Leon C and Layton, Harold E} } @article {wang2009numerical, title = {Numerical simulations of fiber sedimentation in Navier-Stokes flows}, journal = {Communications in Computational Physics}, volume = {5}, number = {1}, year = {2009}, pages = {61}, author = {Wang, Jin and Layton, Anita} } @article {layton2009dorsal, title = {of dorsal closure Drosophila morphogenesis: tissue force laws and the modeling This article describes a second generation mathematical model to investigate the forces that account for the dynamics of dorsal closure, a stage of Drosophila development which}, journal = {HFSP Journal}, number = {6}, year = {2009}, pages = {441}, author = {Layton, Anita T and Toyama, Yusuke and Yang, Guo-Qiang and Edwards, Glenn S and Kiehart, Daniel P and Venakides, Stephanos} } @article {layton2009using, title = {Using integral equations and the immersed interface method to solve immersed boundary problems with stiff forces}, journal = {Computers \& fluids}, volume = {38}, number = {2}, year = {2009}, pages = {266{\textendash}272}, publisher = {Pergamon}, author = {Layton, Anita T} } @article {beale2009velocity, title = {A velocity decomposition approach for moving interfaces in viscous fluids}, journal = {Journal of Computational Physics}, volume = {228}, number = {9}, year = {2009}, pages = {3358{\textendash}3367}, publisher = {Elsevier}, author = {Beale, J Thomas and Layton, Anita T} } @article {layton2009waveform, title = {Waveform distortion in TGF-mediated limit-cycle oscillations: Effects of TAL flow}, journal = {The FASEB Journal}, volume = {23}, year = {2009}, pages = {804{\textendash}14}, publisher = {Federation of American Societies for Experimental Biology}, author = {Layton, Anita T and Moore, Leon C and Layton, Harold E} } @article {layton2008choice, title = {On the choice of correctors for semi-implicit Picard deferred correction methods}, journal = {Applied Numerical Mathematics}, volume = {58}, number = {6}, year = {2008}, pages = {845{\textendash}858}, publisher = {Elsevier}, author = {Layton, Anita T} } @article {layton2008efficient, title = {An efficient numerical method for the two-fluid Stokes equations with a moving immersed boundary}, journal = {Computer methods in applied mechanics and engineering}, volume = {197}, number = {25-28}, year = {2008}, pages = {2147{\textendash}2155}, publisher = {North-Holland}, author = {Layton, Anita T} } @article {pannabecker2008role, title = {Role of three-dimensional architecture in the urine concentrating mechanism of the rat renal inner medulla}, journal = {American Journal of Physiology-Renal Physiology}, volume = {295}, number = {5}, year = {2008}, pages = {F1271{\textendash}F1285}, publisher = {American Physiological Society}, author = {Pannabecker, Thomas L and Dantzler, William H and Layton, Harold E and Layton, Anita T} } @booklet {pannabecker2008three, title = {Three-dimensional reconstructions of rat renal inner medulla suggest two anatomically separated countercurrent mechanisms for urine concentration}, year = {2008}, publisher = {Federation of American Societies for Experimental Biology}, author = {Pannabecker, Thomas Lloyd and Dantzler, William H and Layton, Anita T and Layton, Harold E} } @booklet {layton2008tubuloglomerular, title = {Tubuloglomerular feedback signal transduction in a model of a compliant thick ascending limb}, year = {2008}, publisher = {Federation of American Societies for Experimental Biology}, author = {Layton, Harold E and Moore, Leon C and Layton, Anita T} } @article {beale2007accuracy, title = {On the accuracy of finite difference methods for elliptic problems with interfaces}, journal = {Communications in Applied Mathematics and Computational Science}, volume = {1}, number = {1}, year = {2007}, pages = {91{\textendash}119}, publisher = {Mathematical Sciences Publishers}, author = {Beale, Thomas and Layton, Anita} } @article {layton2007implications, title = {Implications of the choice of predictors for semi-implicit Picard integral deferred correction methods}, journal = {Communications in Applied Mathematics and Computational Science}, volume = {2}, number = {1}, year = {2007}, pages = {1{\textendash}34}, publisher = {Mathematical Sciences Publishers}, author = {Layton, Anita and Minion, Michael} } @booklet {marcano2007maximum, title = {Maximum Urine Concentrating Capability for Transport Parameters and Urine Flow within Prescribed Ranges}, year = {2007}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Marcano, Mariano and Layton, Anita T and Layton, Harold E} } @booklet {layton2007mechanism, title = {A mechanism for the generation of harmonics in oscillations mediated by tubuloglomerular feedback}, year = {2007}, publisher = {The Federation of American Societies for Experimental Biology}, author = {Layton, Harold E and Layton, Anita T and Moore, Leon C} } @article {layton2007role, title = {Role of UTB urea transporters in the urine concentrating mechanism of the rat kidney}, journal = {Bulletin of mathematical biology}, volume = {69}, year = {2007}, pages = {887{\textendash}929}, publisher = {Springer-Verlag}, author = {Layton, Anita T} } @booklet {layton2006dynamics, title = {Dynamics in coupled nephrons may contribute to irregular flow oscillations in spontaneously hypertensive rats}, year = {2006}, publisher = {Federation of American Societies for Experimental Biology}, author = {Layton, Anita T and Moore, Leon C and Layton, Harold E} } @booklet {marcano2006estimation, title = {Estimation of Collecting Duct Parameters for Maximum Urine Concentrating Capability in a Mathematical Model of the Rat Inner Medulla}, year = {2006}, publisher = {Federation of American Societies for Experimental Biology}, author = {Marcano, Mariano and Layton, Anita T and Layton, Harold E} } @booklet {moore2006evidence, title = {Evidence for Multi-Stability of the Tubuloglomerular Feedback System in Spontaneously-Hypertensive Rats (SHR)}, year = {2006}, publisher = {Federation of American Societies for Experimental Biology}, author = {Moore, Leon C and Siu, Kin L and Layton, Anita T and Layton, Harold E and Chon, Ki H} } @booklet {layton2006explicit, title = {An explicit jump method for the two-fluid stokes equations with an immersed elastic boundary}, year = {2006}, publisher = {Elsevier Science}, author = {Layton, Anita T} } @article {thomas2006kidney, title = {Kidney modeling: Status and perspectives}, journal = {Proceedings of the IEEE}, volume = {94}, number = {4}, year = {2006}, pages = {740{\textendash}752}, publisher = {IEEE}, author = {Thomas, S Randall and Layton, Anita T and Layton, Harold E and Moore, Leon C} } @article {layton2006modeling, title = {Modeling water transport across elastic boundaries using an explicit jump method}, journal = {SIAM Journal on Scientific Computing}, volume = {28}, number = {6}, year = {2006}, pages = {2189{\textendash}2207}, publisher = {Society for Industrial and Applied Mathematics}, author = {Layton, Anita T} } @article {marcano2006optimization, title = {An optimization algorithm for a distributed-loop model of an avian urine concentrating mechanism}, journal = {Bulletin of mathematical biology}, volume = {68}, year = {2006}, pages = {1625{\textendash}1660}, publisher = {Springer-Verlag}, author = {Marcano, Mariano and Layton, Anita T and Layton, Harold E} } @article {layton2006quadratic, title = {Quadratic spline Galerkin method for the shallow water equations on the sphere}, journal = {Math. Comput. Simulat}, volume = {71}, year = {2006}, pages = {175{\textendash}186}, author = {Layton, Anita T and Christara, CC and Jackson, KR} } @article {layton2006quadratic, title = {Quadratic spline methods for the shallow water equations on the sphere: Collocation}, journal = {Mathematics and Computers in Simulation}, volume = {71}, number = {3}, year = {2006}, pages = {187{\textendash}205}, publisher = {Elsevier}, author = {Layton, Anita T and Christara, Christina C and Jackson, Kenneth R} } @article {layton2006quadratic, title = {Quadratic spline methods for the shallow water equations on the sphere: Galerkin}, journal = {Mathematics and Computers in Simulation}, volume = {71}, number = {3}, year = {2006}, pages = {175{\textendash}186}, publisher = {Elsevier}, author = {Layton, Anita T and Christara, Christina C and Jackson, Kenneth R} } @article {layton2005implications, title = {Implications of the choice of quadrature nodes for Picard integral deferred corrections methods for ordinary differential equations}, journal = {BIT Numerical Mathematics}, volume = {45}, number = {2}, year = {2005}, pages = {341{\textendash}373}, publisher = {Springer-Verlag}, author = {Layton, Anita T and Minion, Michael L} } @conference {layton2005mathematical, title = {A mathematical model of the urine concentrating mechanism of the inner medulla of the chinchilla kidney}, booktitle = {FASEB JOURNAL}, volume = {19}, number = {4}, year = {2005}, pages = {A149{\textendash}A149}, publisher = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, organization = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, author = {Layton, AT and Layton, HE} } @article {layton2005methodology, title = {A methodology for tracking solute distribution in a mathematical model of the kidney}, journal = {Journal of Biological Systems}, volume = {13}, number = {04}, year = {2005}, pages = {399{\textendash}419}, publisher = {World Scientific}, author = {Layton, Anita T} } @article {layton2005multistability, title = {Multistability in tubuloglomerular feedback and spectral complexity in spontaneously hypertensive rats}, journal = {American Journal of Physiology-Renal Physiology}, year = {2005}, author = {Layton, Anita T and Moore, Leon C and Layton, Harold E} } @conference {marcano2005optimization, title = {An optimization algorithm for a model of the urine concentrating mechanism in rat inner medulla}, booktitle = {FASEB JOURNAL}, volume = {19}, number = {4}, year = {2005}, pages = {A150{\textendash}A150}, publisher = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, organization = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, author = {Marcano, M and Layton, AT and Layton, HE} } @article {layton2005region, title = {A region-based mathematical model of the urine concentrating mechanism in the rat outer medulla. I. Formulation and base-case results}, journal = {American Journal of Physiology-Renal Physiology}, volume = {289}, number = {6}, year = {2005}, pages = {F1346{\textendash}F1366}, publisher = {American Physiological Society}, author = {Layton, Anita T and Layton, Harold E} } @article {layton2005region, title = {A region-based mathematical model of the urine concentrating mechanism in the rat outer medulla. II. Parameter sensitivity and tubular inhomogeneity}, journal = {American Journal of Physiology-Renal Physiology}, volume = {289}, number = {6}, year = {2005}, pages = {F1367{\textendash}F1381}, publisher = {American Physiological Society}, author = {Layton, Anita T and Layton, Harold E} } @article {layton2005role, title = {Role of structural organization in the urine concentrating mechanism of an avian kidney}, journal = {Mathematical biosciences}, volume = {197}, number = {2}, year = {2005}, pages = {211{\textendash}230}, publisher = {Elsevier}, author = {Layton, Anita T} } @conference {thomas2005towards, title = {Towards a web resource for quantitative renal physiology}, booktitle = {Proceedings of the Physiological Society}, volume = {565}, year = {2005}, pages = {98P}, author = {Thomas, S Randall and Layton, Harold E and Layton, Anita T and Harris, Peter and Lonie, Andrew and Moore, Leon C} } @article {layton2004conservative, title = {Conservative multi-implicit integral deferred correction methods with adaptive mesh refinement}, year = {2004}, author = {Layton, Anita T} } @article {layton2004conservative, title = {Conservative multi-implicit spectral deferred correction methods for reacting gas dynamics}, journal = {Journal of Computational Physics}, volume = {194}, number = {2}, year = {2004}, pages = {697{\textendash}715}, publisher = {Elsevier}, author = {Layton, Anita T and Minion, Michael L} } @conference {layton2004effects, title = {Effects of structural organization on the urine concentrating mechanism of the rat kidney}, booktitle = {FASEB JOURNAL}, volume = {18}, number = {5}, year = {2004}, pages = {A1021{\textendash}A1021}, publisher = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, organization = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, author = {Layton, AT and Pannabecker, TL and Dantzler, WH and Layton, HE} } @article {layton2004two, title = {Two modes for concentrating urine in rat inner medulla}, journal = {American Journal of Physiology-Renal Physiology}, volume = {287}, number = {4}, year = {2004}, pages = {F816{\textendash}F839}, publisher = {American Physiological Society}, author = {Layton, Anita T and Pannabecker, Thomas L and Dantzler, William H and Layton, Harold E} } @article {chen2003chauviere, title = {Chauviere, C., 607 Chen, R.-C., 579 Chen, X., 557}, journal = {Journal of Computational Physics}, volume = {189}, year = {2003}, pages = {676}, author = {Chen, Y and Damasceno, JJR and Dance, SL and Dellacherie, S and Evans, TM and Fan, J and Fasso, F and Hewett, DW and Huang, H and Kaul, UK and others} } @article {layton2003efficient, title = {An efficient numerical method for distributed-loop models of the urine concentrating mechanism}, journal = {Mathematical biosciences}, volume = {181}, number = {2}, year = {2003}, pages = {111{\textendash}132}, publisher = {Elsevier}, author = {Layton, Anita T and Layton, Harold E} } @article {bourlioux2003high, title = {High-order multi-implicit spectral deferred correction methods for problems of reactive flow}, journal = {Journal of Computational Physics}, volume = {189}, number = {2}, year = {2003}, pages = {651{\textendash}675}, publisher = {Elsevier}, author = {Bourlioux, Anne and Layton, Anita T and Minion, Michael L} } @conference {layton2003impaired, title = {Impaired countercurrent exchange in a mathematical model of a urine concentrating mechanism lacking UT-B urea transporter.}, booktitle = {JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY}, volume = {14}, year = {2003}, pages = {76A{\textendash}76A}, publisher = {LIPPINCOTT WILLIAMS \& WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA}, organization = {LIPPINCOTT WILLIAMS \& WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA}, author = {Layton, HE and Layton, AT} } @article {johnson2003longevity, title = {Longevity of granular iron in groundwater treatment processes: changes in solute transport properties over time PJ Vikesland, J. Klausen, H. Zimmermann, A. Lynn Roberts and WP Ball............... 3 The effect of local-scale physical heterogeneity and nonl}, journal = {Journal of Contaminant Hydrology}, volume = {64}, year = {2003}, pages = {309{\textendash}310}, author = {Johnson, GR and Gupta, K and Putz, DK and Hu, Q and Brusseau, ML and Richnow, HH and Meckenstock, RU and Reitzel, L Ask and Baun, A and Ledin, A and others} } @conference {layton2003method, title = {A method for tracking solute distribution in mathematical models of the urine concentrating mechanism (UCM)}, booktitle = {FASEB JOURNAL}, volume = {17}, number = {4}, year = {2003}, pages = {A485{\textendash}A485}, publisher = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, organization = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, author = {Layton, AT and Layton, HE} } @article {layton2003region, title = {A region-based model framework for the rat urine concentrating mechanism}, journal = {Bulletin of mathematical biology}, volume = {65}, number = {5}, year = {2003}, pages = {859{\textendash}901}, publisher = {Springer-Verlag}, author = {Layton, Anita T and Layton, Harold E} } @article {layton2003semi, title = {A semi-Lagrangian collocation method for the shallow water equations on the sphere}, journal = {SIAM Journal on Scientific Computing}, volume = {24}, number = {4}, year = {2003}, pages = {1433{\textendash}1449}, publisher = {SIAM}, author = {Layton, Anita T} } @article {layton2003semi, title = {A semi-Lagrangian double Fourier method for the shallow water equations on the sphere}, journal = {Journal of Computational Physics}, volume = {189}, number = {1}, year = {2003}, pages = {180{\textendash}196}, publisher = {Elsevier}, author = {Layton, Anita T and Spotz, William F} } @article {layton2002cubic, title = {Cubic spline collocation method for the shallow water equations on the sphere}, journal = {Journal of Computational Physics}, volume = {179}, number = {2}, year = {2002}, pages = {578{\textendash}592}, publisher = {Elsevier}, author = {Layton, Anita T} } @conference {layton2002internephron, title = {Internephron coupling may contribute to emergence of irregular oscillations mediated by tubuloglomerular feedback.}, booktitle = {JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY}, volume = {13}, year = {2002}, pages = {333A{\textendash}333A}, publisher = {LIPPINCOTT WILLIAMS \& WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA}, organization = {LIPPINCOTT WILLIAMS \& WILKINS 530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA}, author = {Layton, AT and Moore, LC and Layton, HE} } @conference {layton2002mathematical, title = {A mathematical model of the urine concentrating mechanism in the outer medulla of the rat kidney}, booktitle = {FASEB JOURNAL}, volume = {16}, number = {4}, year = {2002}, pages = {A51{\textendash}A51}, publisher = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, organization = {FEDERATION AMER SOC EXP BIOL 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3998 USA}, author = {Layton, AT and Layton, HE} } @article {layton2002numerical, title = {A numerical method for renal models that represent tubules with abrupt changes in membrane properties}, journal = {Journal of mathematical biology}, volume = {45}, number = {6}, year = {2002}, pages = {549{\textendash}567}, publisher = {Springer-Verlag}, author = {Layton, Anita T and Layton, Harold E} } @article {layton2002numerically, title = {A numerically efficient and stable algorithm for animating water waves}, journal = {The Visual Computer}, volume = {18}, year = {2002}, pages = {41{\textendash}53}, publisher = {Springer-Verlag}, author = {Layton, Anita T and van de Panne, Michiel} } @article {layton2002optimal, title = {Optimal quadratic spline collocation methods for the shallow water equations on the sphere}, journal = {Submitted to Mathematics and Computers in Simulation}, year = {2002}, author = {Layton, Anita T and Christara, Christina C and Jackson, Kenneth R} } @article {layton2002semi, title = {A semi-Lagrangian semi-implicit numerical method for models of the urine concentrating mechanism}, journal = {SIAM Journal on Scientific Computing}, volume = {23}, number = {5}, year = {2002}, pages = {1526{\textendash}1548}, publisher = {SIAM}, author = {Layton, Anita T and Layton, Harold E} } @article {modell2001national, title = {A national register for surveillance of inherited disorders: beta thalassaemia in the United Kingdom}, journal = {Bulletin of the World Health Organization}, volume = {79}, number = {11}, year = {2001}, pages = {1006{\textendash}1013}, publisher = {World Health Organization Genebra, Genebra, Switzerland}, author = {Modell, Bernadette and Khan, Maren and Darlison, Matthew and King, Anita and Layton, Mark and Old, John and Petrou, Mary and Varnavides, Lysandros} }