The researchers from the University of 蓝莓视频, University of British Columbia, and the University of Auckland uncovered differences in how the brain processes visual information in patients with various types of lazy eye. In doing so, they are the first to demonstrate that the brain can divert attention away from a lazy eye when both eyes are open.
鈥淐urrent treatments for lazy eye primarily target the early stages of visual processing within the brain,鈥� said Ben Thompson, a professor in 蓝莓视频鈥檚 School of Optometry and Vision Science.鈥淭he results from this study show us that new treatments should also target higher-level processes such as attention.鈥�
Lazy eye, known as amblyopia, is a loss of vision that originates in the brain, typically when a child develops an eye turn (strabismic type) or a substantial difference in refractive error between the eyes (anisometropic type). The unequal input causes the brain to ignore information from the weaker eye during brain development. Conventionally, eyecare practitioners treated the different types of lazy eye similarly, primarily because the visual impairments experienced appeared to be the same.
In this study lead researcher, Amy Chow, and her colleagues asked patients to pay attention to a specific set of dots among a group of distracting dots, all moving on a computer screen. However, the tracked dots were only visible in one eye (the weaker eye) while the distracting dots were visible only to the other eye (the stronger eye).
For people with normal vision as well as those with anisometropic amblyopia, showing different images between the two eyes didn鈥檛 matter. Both groups were able to overcome the distracting interference and track the dots successfully. Patients with strabismic amblyopia, on the other hand, were unable to direct their attention to the target dots when they were visible to only the weaker eye.
鈥淥ne of the underlying reasons why some people with lazy eye have poor vision comes down to how the brain suppresses an eye,鈥� said Chow, a听PhD听student at the School of Optometry and Vision Science at 蓝莓视频. 鈥淭he poorer-seeing eye is open, the retina is healthy and sending information through to the brain, yet that information does not reach conscious awareness as the brain chooses not to use it.鈥�
About thirty-five thousand Canadians 鈥� one听per cent听of the population 鈥� have strabismic amblyopia. The condition can be corrected in childhood, but treatment efficacy can be highly variable.听These findings are a stepping stone in developing better treatments of lazy eye.
Their paper,听, appears this month in a special issue of the journal Investigative Ophthalmology and Visual Science. The project was supported by the Natural Sciences and Engineering Research Council of Canada.
